SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Efficacy and clinical effectiveness of influenza vaccines in HIV-infected individuals: A meta-analysis

2006

BACKGROUND: Though influenza vaccines are the cornerstone of medical interventions aimed at protecting individuals against epidemic influenza, their effectiveness in HIV infected individuals is not certain. With the recent detection...

Barriers to participation in HIV drug trials: A systematic review

2006

The enrolling of adequate participants into HIV experimental drug trials presents an important challenge. We systematically reviewed the literature to identify barriers and concerns amongst HIV patients to participation in...

Effects of music and music therapy on medical patients: A meta-analysis of the research and implications for the future

2006

Although the literature examining the effects of music medicine or music therapy interventions in medical settings is both large and growing, this literature is difficult to summarize because of of...

Do prevention interventions reduce HIV risk behaviours among people living with HIV? A meta-analytic review of controlled trials

2006

Objective: To conduct a meta-analytic review of HIV interventions for people living with HIV (PLWH) to determine their overall efficacy in reducing HIV risk behaviours and identify intervention characteristics associated...

Initial highly-active antiretroviral therapy with a protease inhibitor versus a non-nucleoside reverse transcriptase inhibitor: Discrepancies between direct and indirect meta-analyses

2006

BACKGROUND: The optimum treatment choice between initial highly-active antiretroviral therapy (HAART) with a protease inhibitor (PI) versus a non-nucleoside reverse transcriptase inhibitor (NNRTI) is uncertain. An indirect analysis reported that...

Sputum processing methods to improve the sensitivity of smear microscopy for tuberculosis: A systematic review

2006

In low-income and middle-income countries, direct (unconcentrated) sputum smear microscopy is the primary method for diagnosing pulmonary tuberculosis. The method is fast, inexpensive, and specific for Mycobacterium tuberculosis in high...

A meta-analysis of the relationship of child sexual abuse to HIV risk behavior among women

2005

Objective: This study is a meta-analysis of the literature exploring the relationship between child sexual abuse (CSA) and HIV risk behavior among women. Four outcome variables were tested: unprotected sex;...

A meta-analytic review of HIV behavioral interventions for reducing sexual risk behavior of men who have sex with men

2005

This meta-analysis examines the efficacy of international HIV prevention interventions designed to reduce sexual risk behavior of men who have sex with men (MSM). We performed a comprehensive search of...

Efficacy and safety of cesarean delivery for prevention of mother-to-child transmission of HIV-1

2005

BACKGROUND: Cesarean section before labor and before ruptured membranes (“elective cesarean section”, or ECS) has been introduced as an intervention for the prevention of mother-to-child transmission (MTCT) of HIV-1. The...

Impact of hepatitis C virus on immune restoration in HIV-infected patients who start highly active antiretroviral therapy: A meta-analysis

2005

BACKGROUND: There are conflicting data in the medical literature regarding the degree of immune restoration (as measured by CD4 cell count) in patients who commence highly active antiretroviral therapy (HAART)...

Metaanalysis and metaregression in interpreting study variability in the impact of sexually transmitted diseases on susceptibility to HIV infection

2005

Background: Observational studies examining the effects of other sexually transmitted diseases (STDs) on HIV susceptibility differ in the populations observed and in which “other STDs” are examined. The extent to...

Intravaginal practices, bacterial vaginosis, and women’s susceptibility to HIV infection: Epidemiological evidence and biological mechanisms

2005

Intravaginal practices such as “dry sex” and douching have been suggested as a risk factor that may increase women’s susceptibility to HIV infection. These behaviours appear common in different populations...

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