SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Incidence and risks of HIV infection, medication options, and adverse effects in accidental needle stick injuries: A narrative review

2024

Accidental needle sticks can lead to infections, including HIV. As scientists have learned more about HIV and its replicative physiology, identification of target sites and novel medications have been developed....

The pandemics of mass destruction: A Comparative analysis of HIV/AIDS and Coronavirus (COVID-19)

2024

Historically, humanity has suffered and endured deadly pandemics of varying mortality rates. Irrefutably, research shows that the outbreak of pandemics is flooded by mythical and fallacious information among the public,...

Developing an HIV-specific falls risk prediction model with a novel clinical index: A systematic review and meta-analysis method

2024

Background Falls are a common problem experienced by people living with HIV yet predictive models specific to this population remain underdeveloped. We aimed to identify, assess and stratify the predictive...

Improved outcomes following gastrointestinal surgery among people living with HIV in the HAART-era: A scoping review

2024

Background: This study aimed to review the varied gastrointestinal (GI) system surgical outcomes among people living with Human Immunodeficiency Virus (PLWH) in the HAART-era. Methods: MEDLINE and EMBASE were searched for primary...

Effect of micronutrients on HIV-related clinical outcomes among adults living with HIV on antiretroviral therapy: Systematic review and meta-analysis

2024

Context: Micronutrient deficiencies are common and frequently co-occurring among people living with HIV (PLHIV) globally, with consequences for their health and clinical outcomes. Previous reviews of the influence of micronutrient supplementation...

Community interventions for pandemic preparedness: A scoping review of pandemic preparedness lessons from HIV, COVID-19, and other public health emergencies of international concern

2024

Community action is broadly recognised as central to comprehensive and effective system responses to pandemics. However, there is uncertainty about how and where communities can be best supported to bolster...

Real-world clinical and economic outcomes from rapid start antiretroviral therapy in HIV: Systematic review and meta-analysis

2024

Objective: We aimed to synthesize clinical and economic outcomes of rapid start versus non-rapid antiretroviral therapy (ART) in people with HIV (PWH) in real-world settings. Methods: A search was conducted...

Restarting pre-exposure prophylaxis (PrEP) for HIV: A systematic review and meta-analysis

2024

Background High coverage of pre-exposure prophylaxis (PrEP) will reduce HIV transmission and help end the HIV/AIDS pandemic. However, PrEP users face challenges, including long-term adherence. The study aimed to document...

Prevalence and determinants of under-nutrition among children on ART in Ethiopia: A systematic review and meta-analysis

2024

BACKGROUND: Children living with HIV/AIDS are particularly vulnerable to under-nutrition. Under-nutrition associated with HIV/AIDS infection increases the rate of morbidity and mortality in children. To reaffirm a future objective, there...

Global prevalence and correlates of mpox vaccine acceptance and uptake: A systematic review and meta-analysis

2024

BACKGROUND: Vaccination has been recommended as one of the most potent ways of controlling the mpox (formerly, monkeypox) outbreak, particularly among high-risk groups. Here, we evaluated the prevalence of mpox...

Barriers and facilitators along the PrEP continuum of care among Latinx sexual minoritized men and transgender women: A systematic review

2024

Latinx cisgender sexually minoritized men (SMM) and transgender women (TW) in the U.S. are disproportionately affected by HIV. Although pre-exposure prophylaxis (PrEP) is a highly effective strategy for HIV prevention,...

The viral load monitoring cascade in HIV treatment programmes in sub-Saharan Africa: A systematic review

2024

BACKGROUND: The United Nations’ 95-95-95 (95% of people with HIV being aware of their diagnosis, 95% of those aware of their diagnosis being on treatment and 95% achieving viral suppression)...

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