SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Assessment tools for evaluating pharmacy students’ knowledge on HIV prophylaxis: A scoping review

2025

OBJECTIVES: This study aimed to identify and evaluate instruments used to measure pharmacy students’ knowledge of HIV prophylaxis, focusing on both preexposure prophylaxis (PrEP) and postexposure prophylaxis. METHODS: A systematic...

Pre-exposure prophylaxis uptake among Black/African American men who have sex with other men in Midwestern, United States: A systematic review

2025

INTRODUCTION: Black/African American men who have sex with other men (BMSM) are disproportionately affected by HIV, experience significant disparities in HIV incidence, and face significant barriers to accessing HIV treatment...

HIV infection and antiretroviral therapy impair liver function in people living with HIV: Systematic review and meta-analysis

2025

Background: The use of antiretroviral therapy (ART) has improved the lives of people living with HIV (PLWH). However, its use is associated with secondary complications, notably hepatotoxicity. This systematic review and...

Comparison of treatment-emergent resistance-associated mutations and discontinuation due to adverse events among integrase strand transfer inhibitor-based single-tablet regimens and cabotegravir + rilpivirine for the treatment of virologically suppressed people with HIV: A systematic literature review and network meta-analysis

2025

Objective This study evaluated rates of treatment‐emergent resistance‐associated mutations (TE‐RAMs) and discontinuation due to adverse events (DC‐AEs) across integrase strand transfer inhibitor (INSTI)‐based single‐tablet regimens and injectable cabotegravir + rilpivirine...

Analysis of the effect of the COVID-19 pandemic on syphilis in susceptible populations: Me who have sex with men, people living with HIV, and patients with gestational and congenital syphilis—A narrative review

2025

The COVID-19 pandemic triggered a public health crisis that significantly impacted sexually transmitted infections (STIs), particularly syphilis. However, data on syphilis incidence during the pandemic remains inconsistent globally. Key groups...

Risk perception of human immunodeficiency virus, acquired immune deficiency syndrome, and reproductive health education among among junior and senior high school students: A scoping review

2025

This scoping review aims to identify studies that examine the existence and impact of HIV/AIDs education among high school-aged individuals in Ghana, underscoring the association of factors such as stigma...

Artificial intelligence for HIV care: A global systematic review of current studies and emerging trends

2025

INTRODUCTION: Artificial intelligence (AI) and, in particular, machine learning (ML) have emerged as transformative tools in HIV care, driving advancements in diagnostics, treatment monitoring and patient management. The present review...

Evidence-based interventions targeting mental health problems in adolescents living with HIV: A scoping review

2025

Adolescents living with HIV are at an increased risk of experiencing mental health challenges, impacting their overall well-being and treatment adherence. Evidence-based interventions are crucial to addressing these issues; however,...

HIV testing among transgender and other gender-diverse persons in the United States: A scoping review

2025

BACKGROUND: An overview of existing research on HIV testing among transgender and other gender-diverse (TGD) populations in the United States, critical for developing effective future interventions and research, is missing....

Lessons from the field: A systematic review of global and continental prevalence and challenges of people living with HIV (COVID-19)

2025

COVID-19, caused by SARS-CoV-2, accounts for 186 million infections and more than 4 million deaths globally. This systematic review concentrates on the epidemiological profiling of HIV/AIDS, along with the unique...

Pooled prevalence and associated factors of traditional uvulectom among children in Africa: A systematic review and meta-analysis

2025

BACKGROUND: Traditional childhood uvulectomy (TCU) is an unregulated cultural practice associated with significant health risks, including infections, anemia, aspiration, and oral or pharyngeal injuries. The reuse of unsafe tools such...

The impact of the National Syphilis Prevention Program on the prevalence of syphilis among people living with HIV in China: A systematic review and meta-analysis

2025

Introduction: In 2010, China launched the 10-year National Syphilis Prevention and Control Program to curb the spread of syphilis by integrating syphilis screening and treatment with HIV services. Herein, we aimed...

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