SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Systematic review and meta-analysis on the effect of depression on ART adherence among women living with HIV

2024

BACKGROUND: Depression is a very common psychiatric disorder in worldwide. Globally, Human Immunodeficiency Virus (HIV) is highly prevalent among women, and are disproportionately affected by depression. Antiretroviral Therapy (ART) adherence...

Impact of HIV coinfection on tuberculosis treatment outcomes in Ethiopia: A systematic review and meta-analysis

2024

Objectives: Despite the implementation of a short-term direct observation treatment programme, HIV coinfection is one of the main determinants of tuberculosis (TB) treatment success. This meta-analysis was conducted to report the...

Prevalence of co-trimoxazole resistance among HIV-infected individuals in Ethiopia: A systematic review and meta-analysis

2024

Background Co-trimoxazole is used as a prophylaxis for human immunodeficiency virus (HIV) patients to prevent opportunistic infections. Its widespread use results in the emergence of co-trimoxazole resistance, which is a...

Bone loss and fractures in post-menopausal women living with HIV: A narrative review

2024

INTRODUCTION: Post-menopausal women living with Human Immunodeficiency Virus (WLHIV) face an increased risk of bone fractures due to the relationship between HIV-related factors and menopause. This narrative review aims to...

Barriers and facilitators of physical activity in people living with HIV: A systematic review of qualitative studies

2024

BACKGROUND: Most people living with HIV (PLWH) are sedentary. This study aimed to synthesize the findings of qualitative studies to understand barriers and facilitators of physical activity (PA) among PLWH,...

How does intersectionality impact the quality of healthcare services for Black women living with HIV?

2024

Women with HIV are affected more than men by intersecting discriminations. For Black women, additional discrimination can have a detrimental effect on their HIV care. An extended literature review of...

HIV interventions across the care continuum for adolescents in high-burden countries: A systematic review and meta-analysis

2024

BACKGROUND: Adolescents (10-19 years old) have poor outcomes across the prevention-to-treatment HIV care continuum, leading to significant mortality and morbidity. We conducted a systematic review and meta-analysis of interventions that...

Burden of mortality and its predictors among TB-HIV co-infected patients in Ethiopia: Systematic review and meta-analysis

2024

BACKGROUND: Human immunodeficiency virus (HIV) and tuberculosis (TB) are still the two major deadly pandemics globally, causes 167,000 deaths in 2022. The two lethal combinations pose a substantial challenge to...

Ptosis in human immunodeficiency virus-infected patients under long-term antiretroviral treatment

2024

OBJECTIVE: To present cases of ptosis in HIV-1 patients on long-term antiretroviral therapy (ART) and review the existing literature. METHODS: Five HIV-1-positive patients with slowly progressive bilateral ptosis underwent a...

Guidelines for the transfer of people living with HIV attending primary healthcare facilities in South Africa: A scoping review

2024

People living with HIV may move between health facilities: this is called ‘transfer’, and includes up- and down-referral based on clinical condition and lateral transfer (e.g. between primary healthcare [PHC]...

Providing anti-retroviral treatment did not achieve the ambition of ‘Joint united nations program on HIV/AIDS (UNAIDS) among HIV positive patient in Ethiopia’: A systematic review and meta-analysis

2024

INTRODUCTION: Antiretroviral Treatment (ART) has great importance in reducing viral load. Though a global effort was made to suppress viral load, the level of viral load suppression among ART patients...

Incidence rate of mortality and its predictors among tuberculosis and human immunodeficiency virus coinfected patients on antiretroviral therapy in Ethiopia: Systematic review and meta-analysis

2024

Background Tuberculosis (TB) is the leading cause of death among HIV-infected adults and children globally. Therefore, this study was aimed at determining the pooled mortality rate and its predictors among...

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