SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Improving delivery and use of HIV pre-exposure prophylaxis in the US: A systematic review of implementation strategies and adjunctive interventions

2024

Implementation of pre-exposure prophylaxis (PrEP) to prevent HIV transmission is suboptimal in the United States. To date, the literature has focused on identifying determinants of PrEP use, with a lesser...

Psychometric properties of stigma and discrimination measurement tools for persons living with HIV: A systematic review using the COSMIN methodology

2024

BACKGROUND: The development of antiretroviral therapy broadly extends the life expectancy of persons living with HIV (PLHIV). However, stigma and discrimination are still great threat to these individuals and the...

Facilitators and barriers to adherence to anti-retroviral treatment among pregnant or breastfeeding women living with HIV and perinatally infected infants: A scoping review

2024

In 2022, 54% of 1.5 million children (age 0-14) living with HIV had access to anti-retroviral medication (ART). Adherence to ART for pregnant or breastfeeding HIV + women is critical...

Assessing structural racism and discrimination along the pre-exposure prophylaxis continuum: A systematic review

2024

Structural racism and discrimination (SRD) is deeply embedded across U.S. healthcare institutions, but its impact on health outcomes is challenging to assess. The purpose of this systematic literature review is...

Engagement along the PrEP care continuum among men who have sex with men in China: A systematic review and meta-analysis

2024

Pre-exposure prophylaxis (PrEP), including daily oral, on-demand, and long-acting injectable (LAI), is a promising HIV prevention intervention for men who have sex with men (MSM). We conducted a systematic review...

Concept analysis of psychosocial distress among African American and Latine men who have sex with men: Implications for HIV care

2024

AIM: The aim of this study is to provide conceptual clarity on psychosocial distress among African American and Latine men who have sex with men living with human immunodeficiency virus....

Acceptability and use of HIV self-testing among young people in sub-Saharan Africa: A mixed methods systematic review

2024

Background Young people (YP) are disproportionately affected by the HIV pandemic in sub-Saharan Africa (SSA), but testing rates remain low despite global targets of testing 95% of people with HIV...

Global and regional genetic diversity of HIV-1 in 2010-21: Systematic review and analysis of prevalence

2024

Background The extensive global genetic diversity of HIV-1 poses a major challenge to HIV vaccine development. We aimed to determine recent estimates of and changes in the global and regional...

Occupational post-exposure prophylaxis among healthcare workers: A scoping review of factors affecting optimal utilization

2024

INTRODUCTION: Post-exposure prophylaxis (PEP) is an efficacious prevention method when initiated promptly after an HIV exposure. Yet, PEP has been underutilized, even among healthcare workers (HCWs) with occupational exposure in...

HIV, the gut microbiome and clinical outcomes, a systematic review

2024

BACKGROUND: Effective antiretroviral therapy (ART) has improved the life expectancy of people with HIV (PWH). However, this population is now experiencing accelerated age-related comorbidities, contributed to by chronic immune activation...

Excess mortality attributable to AIDS among people living with HIV in high-income countries: A systematic review and meta-analysis

2024

INTRODUCTION: Identifying strategies to further reduce AIDS-related mortality requires accurate estimates of the extent to which mortality among people living with HIV (PLHIV) is due to AIDS-related or non-AIDS-related causes....

Prevention of viral hepatitis and HIV infection among people who inject drugs: A systematic review and meta-analysis

2024

This study aimed to explore the current evidence on preventing blood-borne virus infections among people who inject drugs (PWID). We conducted a comprehensive search across three databases (PubMed, Embase, Cochrane...

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