SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Facilitators and barriers to physical activity in middle-aged and older adult(s) HIV infected persons: A systematic review of qualitative studies

2026

PURPOSE: This study aims to objectively evaluate and synthesize qualitative studies on the facilitators and barriers to PA among middle-aged and older adults living with HIV. METHODS: A systematic search...

Interventions to increase adherence to antiretroviral therapy in people living with HIV—what works? A systematic review and meta-analysis

2026

The Perceptions and Practicalities Approach (PaPA) is a recommended framework for designing medication adherence interventions. Little is known about the utility of the PaPA framework in improving antiretroviral therapy (ART)...

Characterising concerns and misinformation shaping global HIV vaccine confidence and demand: A structured literature search and content analysis

2026

BACKGROUND: Demand for a future HIV vaccine, similar to other vaccines, is vulnerable to misinformation. A number of studies have examined HIV vaccine acceptability and demand, but few have systematically...

Systematic literature review and meta-analysis of INSTI-based antiretroviral therapy single- versus multiple-tablet regimens for the treatment of HIV

2026

Introduction Antiretroviral single-tablet regimens (STRs) have several advantages over multiple-tablet regimens (MTRs), including increased adherence and improved treatment satisfaction for people with HIV (PWH). This analysis has systematically reviewed and...

Effect of omega-3 supplementation on metabolic and inflammatory markers in adults with HIV infection: A systematic review and meta-analysis

2026

Background People living with human immunodeficiency virus (HIV) infection frequently exhibit altered lipid profiles and persistent inflammation that contribute to long-term morbidity. Omega-3 fatty acids are commonly recommended in this population,...

Patients’ perspectives on medication adherence feedback interventions for managing long-term medications: A systematic review of qualitative evidence

2026

INTRODUCTION: Optimising medication usage is a worldwide challenge. While numerous feedback interventions have been developed to address this issue, understanding patients’ perspectives on the use of such interventions to optimise...

Mpox coinfections and clinical manifestation in Africa: A systematic review and meta-analysis

2026

BACKGROUND: Mpox remains a significant public health challenge in Africa, where endemic transmission persists alongside a high burden of other infectious diseases. Although the epidemiology and clinical impact of coinfections...

What tools do we have to end the US HIV epidemic? A review of structural, biomedical and implementation interventions and their potential population impact

2026

INTRODUCTION: The United States Ending the HIV Epidemic (EHE) initiative was always challenged by structural and implementation barriers to HIV care. On top of that, since 2025, there are additional...

Area-based measures of socioeconomic status in studies assessing health outcomes among people living with HIV in Canada and the USA: A scoping review

2026

OBJECTIVE: Area-based measures of socioeconomic status (SES) are increasingly used to study health disparities among people living with HIV (PLWH), with wide variation in how they are defined and applied...

Barriers and facilitators to oral HIV pre-exposure prophylaxis use in Australia: A scoping review comparing findings to Canada, New Zealand, and the United Kingdom

2026

Oral HIV pre-exposure prophylaxis (PrEP) is highly effective, yet various barriers limit its potential as a HIV prevention strategy. This scoping review aimed to identify and quantify determinants of oral...

Factors associated with severity of pulmonary tuberculosis in people living with and without HIV: A systematic review

2026

Introduction Tuberculosis is a leading infectious cause of death and morbidity in people with and without HIV. Better identification of severe forms could help target early interventions to reduce mortality...

HIV in Iraq: Key populations, sociodemographics, transmission modes, present realities, and urgent next steps: A systematic review

2026

Background and Purpose While empirical studies in Iraq have examined sociodemographic characteristics and modes of human immunodeficiency virus (HIV) transmission, including but not limited to those involving key populations, there...

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