SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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PrEP for women in Europe: A systematic literature review

2023

BACKGROUND: Prevention of HIV transmission is fundamental to ending the HIV epidemic. Pre-exposure prophylaxis (PrEP) with oral tenofovir-emtricitabine (TDF-FTC) is an established HIV-prevention method; however, most PrEP services in Europe...

Contribution of low CD4 cell counts and high HIV viral load to the efficacy of preferred first-line antiretroviral regimens for treating HIV infection: A systematic review and meta-analysis

2023

We assessed whether low CD4 count and high viral load (VL) affect the response to currently preferred ART. We performed a systematic review of randomized, controlled clinical trials that analyzed...

The impact of the COVID-19 pandemic on mental health, associated factors and coping strategies in people living with HIV: A scoping review

2023

INTRODUCTION: The COVID-19 pandemic and associated measures implemented by authorities have created additional stressors and increased the risk of psychological illnesses among people living with HIV (PLWH). Yet, there is...

Does the association between stimulant use and high risk sexual behavior vary by injection drug use, sexual minority status, or HIV infection status? A meta-analysis

2023

There is strong evidence linking stimulant use, namely methamphetamine use, to sexual risk behavior among sexual minority men (SMM); we do not, however, have a good understanding of this relationship...

Preferences for oral- vs blood-based human immunodeficiency virus self-testing: A scoping review of the literature

2023

BACKGROUND: The evidence on preferences for oral- vs blood-based human immunodeficiency virus self-testing (HIVST) has been heterogenous and inconclusive. In addition, most evaluations have relied on hypothetical or stated use...

Weight and metabolic outcomes in naïve HIV patients treated with integrase inhibitor-based antiretroviral therapy: A systematic review and meta-analysis

2023

Background: The use of integrase inhibitor-based antiretroviral therapy could be associated with worse weight and metabolic outcomes in patients with HIV infection. Methods: PubMed, EMBASE, and Scopus were searched from inception to...

Microbiological study of periodontal disease in populations with HIV: A systematic review and meta-analysis

2023

BACKGROUND: No systematic review/meta-analysis has been conducted on the microbiological profile associated with the occurrence of periodontitis in patients with HIV. The aim of this study was to evaluate the...

Incidence and prevalence of hepatitis C virus among HIV-negative gay and bisexual men using HIV pre-exposure prophylaxis (PrEP): A systematic review and meta-analysis

2023

BACKGROUND: Gay and bisexual men using HIV pre-exposure prophylaxis (PrEP) are at increased risk for sexually transmissible infections. Hepatitis C virus (HCV) risk among PrEP users is less clear. We...

Can newborn infants with positive HIV soon after birth be diagnosed with intrauterine infection?

2023

BACKGROUND: Mother-to-child transmission (MTCT) of human immunodeficiency virus (HIV) can occur intrauterine, intrapartum, and postpartum. Currently, infants with confirmed positive results in virological tests before 48h of age are defined...

Awareness, accessibility and uptake of pre-exposure prophylaxis (PrEP) among cisgender and transgender women at risk of HIV infection

2023

Key take-home messages

Country ownership and sustainable programming of the HIV response in South Africa: A scoping review

2023

BACKGROUND: Concerns have arisen regarding the extent to which South Africa’s HIV response can be country-owned and sustainable given substantial foreign investment and technical support. OBJECTIVES: To assess the extent...

Mental health problems across the HIV care continuum for adolescents living with HIV in sub-Saharan Africa: A scoping review

2023

Mental health problems (e.g., anxiety, depression) are frequently experienced by adolescents living with HIV (ALWH) and can worsen HIV-related outcomes. This scoping review synthesizes the existing research on ALWHs’ mental...

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