SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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The experience of healthcare workers to HIV pre-exposure prophylaxis (PrEP) implementation in low- and middle-income countries: A systematic review and qualitative meta-synthesis

2023

BACKGROUND: The effectiveness of pre-exposure prophylaxis has been extensively documented. However, there are substantial gaps between the actual implementation of pre-exposure prophylaxis and the ideal goal, especially in low-and middle-income...

A meta-analysis of gray matter volume abnormalities in HIV patients

2023

HIV infection is known to have significant effects on central nervous system. This study conducted a meta-analysis of whole voxel-based morphometry (VBM) in HIV patients (N=435) and HIV-uninfected controls (N=397)....

Social network strategies to distribute HIV self-testing kits: A global systematic review and network meta-analysis

2023

INTRODUCTION: Social network strategies, in which social networks are utilized to influence individuals or communities, are increasingly being used to deliver human immunodeficiency virus (HIV) interventions to key populations. We...

Acceptability, feasibility, and efficacy of telehealth interventions for HIV testing and treatment in adult populations

2023

Introduction: The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) led to the rapid adoption of telehealth to provide HIV care and treatment. However, limited information exists about the...

Prevalence of visceral leishmaniasis among people with HIV: A systematic review and meta-analysis

2023

Leishmaniasis is a parasitic infection expressing different clinical phenotypes. Visceral leishmaniasis (VL) is considered an opportunistic infection among people with human immunodeficiency virus (HIV). The objective of this review was...

The effect of antiretroviral therapy on the periodontal conditions of patients with HIV infection: A systematic review and meta-analysis

2023

Aim: To assess any differences (1) in the prevalence of periodontitis and necrotizing periodontal diseases, specifically necrotizing gingivitis (NG) and necrotizing periodontitis (NP) between HIV patients receiving antiretroviral therapy (HAART) and...

PrEP for women in Europe: A systematic literature review

2023

BACKGROUND: Prevention of HIV transmission is fundamental to ending the HIV epidemic. Pre-exposure prophylaxis (PrEP) with oral tenofovir-emtricitabine (TDF-FTC) is an established HIV-prevention method; however, most PrEP services in Europe...

Contribution of low CD4 cell counts and high HIV viral load to the efficacy of preferred first-line antiretroviral regimens for treating HIV infection: A systematic review and meta-analysis

2023

We assessed whether low CD4 count and high viral load (VL) affect the response to currently preferred ART. We performed a systematic review of randomized, controlled clinical trials that analyzed...

The impact of the COVID-19 pandemic on mental health, associated factors and coping strategies in people living with HIV: A scoping review

2023

INTRODUCTION: The COVID-19 pandemic and associated measures implemented by authorities have created additional stressors and increased the risk of psychological illnesses among people living with HIV (PLWH). Yet, there is...

Does the association between stimulant use and high risk sexual behavior vary by injection drug use, sexual minority status, or HIV infection status? A meta-analysis

2023

There is strong evidence linking stimulant use, namely methamphetamine use, to sexual risk behavior among sexual minority men (SMM); we do not, however, have a good understanding of this relationship...

Preferences for oral- vs blood-based human immunodeficiency virus self-testing: A scoping review of the literature

2023

BACKGROUND: The evidence on preferences for oral- vs blood-based human immunodeficiency virus self-testing (HIVST) has been heterogenous and inconclusive. In addition, most evaluations have relied on hypothetical or stated use...

Weight and metabolic outcomes in naïve HIV patients treated with integrase inhibitor-based antiretroviral therapy: A systematic review and meta-analysis

2023

Background: The use of integrase inhibitor-based antiretroviral therapy could be associated with worse weight and metabolic outcomes in patients with HIV infection. Methods: PubMed, EMBASE, and Scopus were searched from inception to...

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