Category Archives: Cardiovascular

Cardio-metabolic health of offspring exposed in utero to human immuno-deficiency virus and anti-retroviral treatment: A systematic review

2024

BACKGROUND: Antiretroviral treatment (ART) use during pregnancy continues to rise as it is known to decrease the likelihood of HIV transmission from mother to child. However, it is still unknown...

Risk of death and readmission among individuals with heart failure and HIV: A systematic review and meta-analysis

2024

The association between human immunodeficiency virus (HIV) status and readmissions and death outcomes in patients with established heart failure (HF) remains unclear. We conducted a systematic search of PubMed, EMBASE,...

Dyslipidemia among HIV-infected patients in Ethiopia: A systematic review and meta-analysis

2024

Background Dyslipidemia is responsible for more than half of the global ischemic heart disease (IHD) and more than 4 million deaths annually. Assessing the prevalence of dyslipidemia can be crucial...

Prevalence of obesity, hypertension and diabetes among people living with HIV in South Africa: A systematic review and meta-analysis

2023

Background HIV has become a manageable chronic condition due to the success and scale-up of antiretroviral therapy (ART). Globally, South Africa has the highest number of people living with HIV...

Cardiovascular challenges in the era of antiretroviral therapy for AIDS/ HIV: A comprehensive review of research advancements, pathophysiological insights, and future directions

2024

Cardiovascular disease, particularly coronary heart disease, is becoming more common among those living with HIV. Individuals with HIV face an increased susceptibility to myocardial infarction, also known as a heart...

The impact of contemporary antiretroviral drugs on atherosclerosis and its complications in people living with HIV: A systematic review

2023

With thWith the advent of modern antiretroviral therapy (ART), human immunodeficiency virus (HIV) infection has been modified into a chronic manageable condition, prolonging the lifespan of people living with HIV...

The burden of non-communicable diseases among people living with HIV in Sub-Saharan Africa: A systematic review and meta-analysis

2023

BACKGROUND: Non-communicable diseases (NCDs) are increasing among people living with HIV (PLHIV), especially in Sub-Saharan Africa (SSA). We determined the prevalence of NCDs and NCD risk factors among PLHIV in...

Systematic review on cumulative HIV viraemia among people living with HIV receiving antiretroviral treatment and its association with mortality and morbidity

2023

BACKGROUND: We performed a systematic review to generate evidence on the association between cumulative human immunodeficiency virus (HIV) viraemia and health outcomes. METHODS: Quantitative studies reporting on HIV cumulative viraemia...

Prevalence and impact of HIV infections in patients with rheumatic heart disease: A systematic review and meta-analysis

2023

Socioeconomic factors such as poor health and poor nutrition in low- and middle-income countries (LMICs) may favour inflammatory reactions, thus contributing to the recurrence of rheumatic fever (RF) and thereby...

The risk of new heart failure associated with protease inhibitor: Systematic scoping review

2023

BACKGROUND: Protease inhibitors (PIs) have contributed to the long-term survival of persons with human immunodeficiency virus (PHIV). While there is a concern linking protease inhibitors to an increased risk of...

Prevalence and incidence of stroke among people with HIV

2023

Objective: We aimed to obtain more precise estimates of stroke to address the wide variation of stroke burden among people with HIV (PWH) in different clinical settings. Design: Systematic review...

A systematic review and meta-analysis on the impact of statin treatment in HIV patients on antiretroviral therapy

2023

The rate of new human immunodeficiency virus (HIV) infections globally is alarming. Although antiretroviral therapy (ART) improves the quality of life among this group of patients, ARTs are associated with...

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