Category Archives: Co-morbidities

A systematic review of how to reduce morbidity in HIV patients with cardiovascular diseases

2023

The human immunodeficiency virus (HIV) is known to cause cardiovascular diseases in patients infected with HIV. The pathology ranges from atherosclerosis to cardiomyopathy. There are several factors that could possibly...

Prevalence and influences of diabetes and prediabetes among adults living with HIV in Africa: A systematic review and meta-analysis

2023

INTRODUCTION: In people living with human immunodeficiency virus (PLHIV), traditional cardiovascular risk factors, exposure to HIV per se and antiretroviral therapy (ART) are assumed to contribute to cardiometabolic diseases. Nevertheless,...

New onset type 2 diabetes mellitus risks with integrase strand transfer inhibitors-based regimens: A systematic review and meta-analysis

2023

Objectives: The development of diabetes mellitus (DM) in patients taking integrase strand transfer inhibitors (INSTIs) has raised concerns. It’s critical because, in most guidelines, INSTIs are the preferred third agent at...

A systematic review of sarcopenia prevalence and associated factors in people living with human immunodeficiency virus

2023

People living with human immunodeficiency virus (HIV) (PLWH) appear to be at an increased risk of sarcopenia, which can have a devastating effect on their life due to consequences such...

Review of electrocardiographic abnormalities among people living with HIV in Sub-Saharan Africa: A systematic review

2023

INTRODUCTION: Electrocardiographic (ECG) abnormalities are increasingly being reported among people living with HIV (PLWH). However, the exact prevalence of ECG abnormalities among PLWH in Sub-Saharan Africa (SSA), a region with...

Uncovering the NAFLD burden in people living with HIV from high- and middle-income nations: A meta-analysis with a data gap from Subsaharan Africa

2023

INTRODUCTION: Non-alcoholic fatty liver disease (NAFLD) has become a significant concern among people living with HIV (PLHIV), albeit its burden remains unclear. The primary objective of this systematic review (SR)...

Selected inflammatory and coagulation biomarkers pre-viral suppression in people with human immunodeficiency virus (HIV) infection without overt cardiovascular disease: Is there a need to redefine reference indices?

2023

Background Human immunodeficiency virus (HIV) infection is prevalent in Africa and causes morbidity and mortality despite antiretroviral therapy (ART). Non-communicable complications of HIV infection include cardiovascular disease (CVD) with thromboses throughout the vascular tree....

Prediction models for cardiovascular disease risk among people living with HIV: A systematic review and meta-analysis

2023

Background: HIV continues to be a major global health issue. The relative risk of cardiovascular disease (CVD) among people living with HIV (PLWH) was 2.16 compared to non-HIV-infections. The prediction of...

Addressing gaps in cardiovascular care for people with HIV: Bridging scientific evidence and practice

2022

PURPOSE OF REVIEW: People with HIV continue to have an excess burden of cardiovascular disease compared to the general population. The reasons for these disparities in cardiovascular disease include HIV-specific...

Performance of cardiovascular risk prediction models among people living with HIV: A systematic review and meta-analysis

2023

Importance  Extant data on the performance of cardiovascular disease (CVD) risk score models in people living with HIV have not been synthesized. Objective  To synthesize available data on the performance of the...

Cardiovascular disease risk in women living with HIV

2022

PURPOSE OF REVIEW: To synthesize current evidence on the impact of cardiovascular disease among women living with HIV (WLWH) with a particular focus on disease prevalence, mechanisms and prevention. RECENT...

Prevention of heart failure, tachyarrhythmias and sudden cardiac death in HIV

2022

PURPOSE OF REVIEW: To summarize the state-of-the-art literature on the epidemiology, disease progression, and mediators of heart failure, tachyarrhythmias, and sudden cardiac death in people living with HIV (PLWH) to...

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