Category Archives: Epidemiology

Adherence to option B+ antiretroviral therapy and associated factors in pregnant and breastfeeding women in Sub-Saharan Africa: A systematic review and meta-analysis

2024

Background To assess the adherence to option B + antiretroviral therapy (ART) and associated factors in pregnant and breastfeeding women in Sub-Saharan Africa (SSA). Methods We conducted a comprehensive search from 01st January...

Incidence and predictors of loss to follow-up among Ethiopian children on antiretroviral therapy: A systematic review and meta-analysis

2024

Introduction Loss of follow-up (LTFU) from ART regular follow-up is one of the key acknowledged causes for the development of ART-resistant virus strains currently. It becomes a major weakness for...

Apathy in persons living with HIV disease: A systematic narrative review

2024

BACKGROUND: Apathy was identified as a feature of HIV early in the epidemic; however, there are no systematic reviews of the diverse literature on the sociodemographic and clinical correlates of...

Characterization of HIV-1 reservoirs in children and adolescents: A systematic review and meta-analysis toward pediatric HIV cure

2024

Objective: To conduct a comprehensive, systematic review of the profile of HIV-1 reservoirs in children and adolescents with perinatally acquired HIV infection. Study design: Randomized and nonrandomized trials, cohort studies, and cross-sectional...

HIV prevention and treatment interventions for Black men who have sex with men in Canada: Scoping systematic review

2024

BACKGROUND: Black men who have sex with men (MSM) experience disproportionately high HIV incidence globally. A comprehensive, intersectional approach (race, gender, and sexuality or sexual behavior) in understanding the experiences...

Screening and prevention of HPV-related anogenital cancers in women living with HIV in Europe: Results from a systematic review

2024

Background Women living with HIV (WLWH) are at increased risk of human papillomavirus (HPV)-related cancers. Throughout Europe, there is great heterogeneity among guidelines for screening programmes, access to HPV testing...

Prevention of viral hepatitis and HIV infection among people who inject drugs: A systematic review and meta-analysis

2024

This study aimed to explore the current evidence on preventing blood-borne virus infections among people who inject drugs (PWID). We conducted a comprehensive search across three databases (PubMed, Embase, Cochrane...

Syphilis epidemic among men who have sex with men: A global systematic review and meta-analysis of prevalence, incidence, and associated factors

2024

BACKGROUND: We aimed to estimate the prevalence and incidence of syphilis at global, regional and national levels for human immunodeficiency virus (HIV)-positive and HIV-negative men who have sex with men...

Major drug resistance mutations on reverse transcriptase gene in human immunodeficiency virus type-1 in Indonesia: A systematic review

2024

PURPOSE OF REVIEW: The prevalence of HIV-1 in Indonesia is on a concerning upward trajectory, with a concurrent rise in the development of drug-resistant strains, challenging the efficacy of antiretroviral...

Counseling supporting HIV self-testing and linkage to care among men who have se with men: Systematic review and meta-analysis

2024

BACKGROUND: Counseling supporting HIV self-testing (HIVST) is helpful in facilitating linkage to care and promoting behavior changes among men who have sex with men (MSM). Different levels of counseling support...

Patient-reported outcome measures in adult HIV care: A rapid scoping review of targeted outcomes and instruments used

2024

Objective There is international interest in the integration of patient-reported outcome measures (PROMs) into routine HIV care, but little work has synthesized the content of published initiatives. We conducted a...

Weight loss and mortality in people living with HIV: A systematic review and meta-analysis

2024

Background In the first reported cases of human immunodeficiency virus (HIV) infection, people living with HIV (PLHIV) suffered weight loss, which was an independent predictor of mortality. Highly active antiretroviral...

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