Category Archives: Epidemiology

A scoping review on HIV early infant diagnosis among HIV exposed infants, ART use and adherence in Tanzania

2023

BACKGROUND: HIV Early Infant Diagnosis (HEID) is critical for the timely initiation of HIV treatments and improved health outcomes among HIV-infected infants. However, the uptake of HEID remains largely low...

A meta-analysis of immunogenicity and safety of two versus single-doses of influenza A (H1N1) vaccine in person living with HIV

2023

Purpose: Influenza vaccination of person living with HIV (PLWH) is a powerful means to tackle severe clinical outcomes. Few data on two doses of influenza vaccine in PLWH are available.Research...

Pre-exposure prophylaxis adherence among men who have sex with men: A systematic review and meta-analysis

2024

OBJECTIVES: The effectiveness and efficiency of pre-exposure prophylaxis (PrEP) in reducing the transmission of HIV among men who have sex with men (MSM) relies on how widely it is adopted...

Frequency of fungal pathogens in autopsy studies of people who died with HIV in Africa: A scoping review

2023

Background: Fungal infections are common in HIV-infected individuals and significantly contribute to mortality. However, a substantial number of cases are undiagnosed before death. Objective: To determine the frequency of fungal pathogens in...

Fixed-dose antiretroviral combinations in children living with human immunodeficiency virus type 1 (HIV-1): A systematic review

2023

Fixed-Dose antiretroviral Combinations (FDCs) are the most used drug regimes in adult patients with human-immunodeficiency virus 1 infection, since they increase adherence to antiretroviral therapy and enable good quality of...

Non-adherence to anti-retroviral therapy among adult people living with HIV in Ethiopia: Systematic review and meta-analysis

2023

Human immunodeficiency virus remains a global public health problem. Despite efforts to determine the prevalence of non-adherence to ART and its predictors in Ethiopia, various primary studies presented inconsistent findings....

Geographic and population distributions of human immunodeficiency virus (HIV)-1 and HIV-2 circulating subtypes: A systematic literature review and meta-analysis (2010–2021)

2023

BACKGROUND: HIV poses significant challenges for vaccine development due to its high genetic mutation and recombination rates. Understanding the distribution of HIV subtypes (clades) across regions and populations is crucial....

Barriers and facilitators for interventions to improve ART adherence in Sub-Saharan African countries: A systematic review and meta-analysis

2023

BACKGROUND: The HIV/AIDS pandemic remains a significant public health issue, with sub-Saharan Africa (SSA) at its epicentre. Although antiretroviral therapy (ART) has been introduced to decrease new infections and deaths,...

The association of women’s empowerment with HIV-related indicators: A pooled analysis of demographic and health surveys in sub-Saharan Africa

2023

Background Women’s empowerment is an important factor for HIV prevention, but the association with HIV-related indicators has never been quantified. In this study, we examined the association between women’s empowerment...

Digital epidemiological approaches in HIV research: A scoping methodological review

2023

PURPOSE OF REVIEW: The purpose of this scoping review was to summarize literature regarding the use of user-generated digital data collected for non-epidemiological purposes in human immunodeficiency virus (HIV) research....

Global, regional, and country-level coverage of testing and treatment for HIV and hepatitis C infection among people who inject drugs: A systematic review

2023

Background People who inject drugs are disproportionately affected by HIV and hepatitis C virus (HCV) infections, while there is little global data on HIV and HCV testing and treatment coverage...

A literature review on the adherence to screening guidelines for latent tuberculosis infection among persons living with HIV

2023

Human immunodeficiency virus (HIV) infection increases the risk of reactivation of latent tuberculosis infection (LTBI). Although antiretroviral therapy decreases the progression of LTBI to tuberculosis disease (TBD), persons living with...

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