Category Archives: Epidemiology
Differences in breastfeeding duration by maternal HIV status: A pooled analysis of nationally representative surveys in sub-Saharan Africa
BACKGROUND: Breastfeeding improves child survival but is a source of mother-to-child HIV transmission among women with unsuppressed HIV infection. Estimated HIV incidence in children is sensitive to breastfeeding duration among...
Providing anti-retroviral treatment did not achieve the ambition of ‘Joint united nations program on HIV/AIDS (UNAIDS) among HIV positive patient in Ethiopia’: A systematic review and meta-analysis
INTRODUCTION: Antiretroviral Treatment (ART) has great importance in reducing viral load. Though a global effort was made to suppress viral load, the level of viral load suppression among ART patients...
Prevalence of obesity, hypertension and diabetes among people living with HIV in South Africa: A systematic review and meta-analysis
Background HIV has become a manageable chronic condition due to the success and scale-up of antiretroviral therapy (ART). Globally, South Africa has the highest number of people living with HIV...
Adverse effects of daily oral pre-exposure prophylaxis in men who have sex with men and transgender women: A systematic review and meta-analysis
The adverse effects of oral pre-exposure prophylaxis (PrEP) using tenofovir disoproxil fumarate are barriers to PrEP initiation and continuation. Although serious effects are rare and predictable, evidence for this assessment...
Systematic review and meta-analysis of seroprevalence of human immunodeficiency virus serological markers among pregnant women in Africa, 1984–2020
BACKGROUND: Human immunodeficiency virus (HIV) is a major public health concern, particularly in Africa where HIV rates remain substantial. Pregnant women are at an increased risk of acquiring HIV, which...
A scoping review on HIV early infant diagnosis among HIV exposed infants, ART use and adherence in Tanzania
BACKGROUND: HIV Early Infant Diagnosis (HEID) is critical for the timely initiation of HIV treatments and improved health outcomes among HIV-infected infants. However, the uptake of HEID remains largely low...
A meta-analysis of immunogenicity and safety of two versus single-doses of influenza A (H1N1) vaccine in person living with HIV
Purpose: Influenza vaccination of person living with HIV (PLWH) is a powerful means to tackle severe clinical outcomes. Few data on two doses of influenza vaccine in PLWH are available.Research...
Pre-exposure prophylaxis adherence among men who have sex with men: A systematic review and meta-analysis
OBJECTIVES: The effectiveness and efficiency of pre-exposure prophylaxis (PrEP) in reducing the transmission of HIV among men who have sex with men (MSM) relies on how widely it is adopted...
Frequency of fungal pathogens in autopsy studies of people who died with HIV in Africa: A scoping review
Background: Fungal infections are common in HIV-infected individuals and significantly contribute to mortality. However, a substantial number of cases are undiagnosed before death. Objective: To determine the frequency of fungal pathogens in...
Fixed-dose antiretroviral combinations in children living with human immunodeficiency virus type 1 (HIV-1): A systematic review
Fixed-Dose antiretroviral Combinations (FDCs) are the most used drug regimes in adult patients with human-immunodeficiency virus 1 infection, since they increase adherence to antiretroviral therapy and enable good quality of...