Category Archives: Epidemiology and Determinants of Health
The intersection of mental health and sexual and gender minority identities for older adults living with Human Immunodeficiency Virus: A narrative review
The transition of HIV into a chronic illness has brought to the forefront the pressing need to address the complex web of social determinants of HIV outcomes. A structured literature...
Psychometric properties of stigma and discrimination measurement tools for persons living with HIV: A systematic review using the COSMIN methodology
BACKGROUND: The development of antiretroviral therapy broadly extends the life expectancy of persons living with HIV (PLHIV). However, stigma and discrimination are still great threat to these individuals and the...
The link between anticipated and internalized stigma and depression: A systematic review
Stigmatized groups may experience psychological distress. Yet, some studies show no significant relation between stigma and mental health outcomes. This systematic review investigates the link between anticipated and internalized stigma,...
Perinatal outcomes associated with pre-exposure prophylaxis for HIV prevention during pregnancy: A systematic review and meta-analysis
Background The World Health Organization (WHO) recommends tenofovir disoproxil fumarate (TDF)-based oral pre-exposure prophylaxis (PrEP), the dapivirine vaginal ring, and long-acting intramuscular injectable cabotegravir (CAB-LA) for HIV prevention in populations...
Prevalence of emergent dolutegravir resistance mutations in people living with HIV: A rapid scoping review
BACKGROUND: Dolutegravir (DTG) is a cornerstone of global antiretroviral (ARV) therapy (ART) due to its high efficacy and favorable tolerability. However, limited data exist regarding the risk of emergent integrase...
Prevalence, clinical features, and predictors of adrenal insufficiency in adults with tuberculosis or HIV: A systematic review and meta-analysis
BACKGROUND: Despite the high frequency of adrenal insufficiency (AI) in patients with tuberculosis or HIV, its diagnosis is often missed or delayed resulting in increased mortality. This systematic review and...
Improving delivery and use of HIV pre-exposure prophylaxis in the US: A systematic review of implementation strategies and adjunctive interventions
Implementation of pre-exposure prophylaxis (PrEP) to prevent HIV transmission is suboptimal in the United States. To date, the literature has focused on identifying determinants of PrEP use, with a lesser...
Severity of COVID-19 manifestations in HIV patients: A systematic review and meta-analysis
OBJECTIVE: The incidence of coronavirus disease 2019 (COVID-19) pandemic among people living with HIV (PLWH) is experiencing major increases. This demographic is vulnerable due to compromised immune function, but the...
Impact of maternal HIV infection on perinatal outcomes: A systematic review
BACKGROUND: Maternal HIV infection remains a significant global health concern with potential repercussions on perinatal outcomes. Emphasis on early intervention to improve peri- and postnatal outcomes in infected mothers and...
Interventions for integrating behavioral health into HIV settings for US adults: A narrative review of systematic reviews and meta-analyses, 2010–2020
Mental health and substance use disorders can negatively affect physical health, illness management, care access, and quality of life. These behavioral health conditions are prevalent and undertreated among people with...
Comparative efficacy and safety of Pneumocystis jirovecii pneumonia prophylaxis regimens for people living with HIV: A systematic review and network meta-analysis of randomized controlled trials
Background Pneumocystis jirovecii pneumonia (PCP) is a common opportunistic infection among people living with HIV (PWH), particularly among new and untreated cases. Several regimens are available for the prophylaxis of PCP, including...
Improved outcomes following gastrointestinal surgery among people living with HIV in the HAART-era: A scoping review
Background: This study aimed to review the varied gastrointestinal (GI) system surgical outcomes among people living with Human Immunodeficiency Virus (PLWH) in the HAART-era. Methods: MEDLINE and EMBASE were searched for primary...
