Category Archives: Epidemiology and Determinants of Health
Global prevalence of depressive symptoms among people living with HIV/AIDS: A systematic review and meta-analysis of the past five years
A clear and accurate assessment of depressive symptoms among people living with HIV/AIDS (PLWHA) in the past five years is essential to help develop reasonable and sound interventions to improve...
Endothelial dysfunction, a predictor of cardiovascular disease in HIV patients on antiretroviral therapy: A systematic review and meta-analysis
Aim Although antiretroviral therapy (ART) is available, the rate of new HIV infections is alarming. With this trend, it is anticipated that the use of ART will continue to rise,...
Recent advances in HIV-associated neurocognitive disorders: A focus on older adults and sub-Saharan Africa
PURPOSE OF REVIEW: We reviewed recent literature on prevalence and interventional approaches for cognitive impairment in the context of HIV infection alongside current controversies and challenges around its nomenclature, screening,...
Effect of intake of probiotics and probiotic fermented foods on clinical outcomes among people living with HIV: A systematic review and meta-analysis
OBJECTIVE: The objective of the study was to determine the effect of probiotics and of probiotic-fermented foods on CD4 T-cell count, viral load, anaemia and body mass index (BMI) among...
Syphilis prevalence among people living with and without HIV in sub-Saharan Africa: A systematic review and meta-analysis
BACKGROUND: Syphilis is a curable sexually transmitted infection which, untreated, is associated with significant morbidity and mortality. In people living with HIV (PLWH), syphilis carries greater risks of disease progression....
Regional variation in NAFLD prevalence and risk factors among people living with HIV in Europe: A meta-analysis
BACKGROUND AND AIM: Europe faces an elevated risk of nonalcoholic fatty liver disease (NAFLD) among people living with HIV (PLWH), contributing to the region’s highest global burden of NAFLD. However,...
Adherence to option B+ antiretroviral therapy and associated factors in pregnant and breastfeeding women in Sub-Saharan Africa: A systematic review and meta-analysis
Background To assess the adherence to option B + antiretroviral therapy (ART) and associated factors in pregnant and breastfeeding women in Sub-Saharan Africa (SSA). Methods We conducted a comprehensive search from 01st January...
Incidence and predictors of loss to follow-up among Ethiopian children on antiretroviral therapy: A systematic review and meta-analysis
Introduction Loss of follow-up (LTFU) from ART regular follow-up is one of the key acknowledged causes for the development of ART-resistant virus strains currently. It becomes a major weakness for...
Characterization of HIV-1 reservoirs in children and adolescents: A systematic review and meta-analysis toward pediatric HIV cure
Objective: To conduct a comprehensive, systematic review of the profile of HIV-1 reservoirs in children and adolescents with perinatally acquired HIV infection. Study design: Randomized and nonrandomized trials, cohort studies, and cross-sectional...
