Category Archives: Epidemiology and Determinants of Health
Exploring barriers to antiretroviral therapy adherence among pregnant women: A scoping literature review
BACKGROUND: Antiretroviral therapy (ART) is one of the most effective ways of preventing HIV-related maternal mortality. However, the rates of retention in care and long-term adherence remain extremely low. OBJECTIVE:...
A systematic review of factors critical for HIV health literacy, ART adherence and retention in care in the U.S. for racial and ethnic minorities
Despite advances in antiretroviral treatment (ART), the HIV epidemic persists in the United States (U.S.), with inadequate adherence to treatment and care a major barrier to ending the epidemic. Health...
An overview of Patient Advisory Councils and Community Advisory Councils in health care
Key take-home messages Patient Advisory Councils and Community Advisory Councils promote patient engagement and the development of strategies and interventions to benefit the delivery of patient care; these collaborative councils...
Early neurodevelopment of HIV-exposed uninfected children in the era of antiretroviral therapy: A systematic review and meta-analysis
Background: There are 15·4 million children who are HIV-exposed and uninfected worldwide. Early child development crucially influences later academic and socioeconomic factors. However, the neurodevelopmental outcomes of HIV-exposed uninfected (HEU) children...
Efficacy of covid-19 vaccines in immunocompromised patients: Systematic review and meta-analysis
Objective: To compare the efficacy of covid-19 vaccines between immunocompromised and immunocompetent people. Design: Systematic review and meta-analysis. Data sources: PubMed, Embase, Central Register of Controlled Trials, COVID-19 Open Research Dataset Challenge (CORD-19),...
Detection of HIV virologic failure and switch to second-line therapy: A systematic review and meta-analysis of data from sub-Saharan Africa
BACKGROUND: The late recognition of virologic failure (VF) places persons with HIV in Sub-Saharan Africa at risk for HIV transmission, disease progression, and death. We conducted a systematic review and...
Treatment failure and its associated factors among children receiving highly active antiretroviral therapy in Ethiopia: A systematic review and meta-analysis
OBJECTIVES: Over the last decades, large number of children living with human immunodeficiency virus (HIV) have been successfully enrolled in care and initiated treatment. However, treatment failure is still a...
Meta-synthesis and science mapping analysis of HIV/HPV co-infection: A global perspective with emphasis on Africa
BACKGROUND: Viral infections are emerging with diverse clinical relevance both in endemic environments and non-endemic regions of the world. Some of the viruses cause co-infections that are of public health...
The impact of tuberculosis co-infection on virological failure among adults living with HIV in Ethiopia: A systematic review and meta-analysis
Introduction: Tuberculosis (TB) is the most common serious opportunistic infection among people with Human Immunodeficiency Virus (HIV) infection and are considered as the double burden diseases of the world. TB is...
Prevalence of frailty and prefrailty in people with human immunodeficiency virus aged 50 or older: A systematic review and meta-analysis
Background: With effective antiretroviral therapy, there is an emerging population of adults aged 50 years or older with human immunodeficiency virus (HIV). Frailty is an increasingly recognized clinical state of vulnerability...
