Category Archives: Neurocognitive disorders
Possible prevention of neurodevelopmental consequences of vertical HIV transmission in early childhood? A systematic review
BACKGROUND: Children infected with the Human Immunodeficiency Virus (HIV) exhibit the lowest neurodevelopmental scores. Mother-to-child-transmission prevention include perinatally and early antiretroviral therapy (ART) although long-term effects of in utero exposure...
Association between cerebrospinal fluid CXCL10 and neurocognitive disorders in people living with HIV: A meta-analysis
Background C-X-C motif chemokine ligand 10 (CXCL10) is implicated in HIV-associated neuroinflammation, yet its association with HIV-associated neurocognitive disorders (HAND) remains unclear. We conducted a meta-analysis to evaluate cerebrospinal fluid...
Challenges to physical activity participation among older people living with HIV: Scoping review
Older people living with Human Immunodeficiency Virus (OPLWH) have lower physical activity levels than other population groups. Inadequate physical activity participation increases the risks of age-related non-communicable diseases (NCDs). Therefore,...
Divergent structural and functional brain alterations in HIV-infected patients: A multimodal meta-analysis
Neuroimaging studies have identified brain structural and functional alterations in HIV-infected patients; however, the results are inconsistent. This study aimed to characterize the effects of HIV infection on regional gray...
Studies on cognitive performance among older people living with HIV in eastern Europe and central Asia: A scoping review
BACKGROUND: Despite the growth of the population of older people living with HIV (PLWH), data on cognitive disorders among older PLWH, particularly in low- and middle-income countries, are scarce. These...
Aging and HIV: Recent findings in contributing factors
Background: Aging among people living with HIV (PLWH) presents multifaceted challenges influenced by antiretroviral therapy (ART), chronic inflammation, viral coinfections, stigma, multimorbidity, and immunosuppression. Methods: This review synthesizes recent research...
Development of research on HIV-associated neurocognitive disorder and emerging trends: a visualization analysis via CiteSpace
BACKGROUND: In the combination antiretroviral therapy era, HIV-associated neurocognitive disorder (HAND) is still widespread among HIV-infected individuals. However, there is no effective treatment for HAND, and the exact pathogenic mechanism...
Prevalence of mental health problems in people living with HIV: A systematic review and meta-analysis
HIV remains a significant public health concern, with an estimation of 39 million people infected. There is a lack of universally accepted benchmarks for prevalence of mental health problems among...
Non-pharmaceutical interventions for people living with HIV with cognitive impairment: A scoping review
BACKGROUND: Cognitive impairment (CI) in HIV is often of multifactorial causation, and remains a prominent issue in the age of effective combination antiretroviral therapy (cART), affecting approximately 14% of people...
Neuropsychiatric outcomes in children and adolescents with perinatally acquired HIV: A systematic review and meta analysis
Objective: The objective of this study is to define the neuropsychiatric challenges including developmental delay, cognitive impairment, and psychiatric illness faced by children with perinatally acquired HIV. Data sources: Nine databases were...
