Category Archives: Population(s)

Association between rectal gonorrhoea and HIV incidence in men who have sex with men: A meta-analysis

2021

Background: Incidence of rectal gonorrhoea (GC) has been hypothesised as a correlate of HIV exposure in prevention trials of men who have sex with men (MSM). High rectal GC incidence in...

Is tenofovir disoproxil fumarate associated with weight loss?

2021

Background: Recent clinical trials have shown weight gain associated with newer antiretrovirals. It is unclear how the nucleoside reverse transcriptase inhibitor backbone affects weight. Recent evidence suggests greater weight gain with...

Global burden and changing trend of hepatitis C virus infection in HIV-positive and HIV-negative MSM: A systematic review and meta-analysis

2021

Background: The disease burden of hepatitis C virus (HCV) infection in HIV-positive and HIV-negative men who have sex with men (MSM) is changing. We aim to provide an updated comprehensive...

HIV/AIDS late presentation and its associated factors in China from 2010 to 2020: A systematic review and meta-analysis

2021

Background Late presentation to HIV/AIDS care presents serious health concerns, like increased transmission and high healthcare costs, increased mortality, early development of opportunistic infection, increased risk of antiretroviral therapy drug...

Influence of material deprivation on clinical outcomes among people living with HIV in high-income countries: A systematic review and meta-analysis

2021

Despite developments in HIV treatment and care, disparities persist with some not fully benefiting from improvements in the HIV care continuum. We conducted a systematic review to explore associations between...

“Slam Sex”—Sexualized Injecting Drug Use (“SIDU”) Amongst Men Who Have Sex with Men (MSM)—A Scoping Review

2021

Sexualized injecting drug use (“SIDU”) is a phenomenon associated with a wide array of high-risk injecting and sex-related practices. This scoping review establishes what is known about MSM and SIDU...

Immune response to hepatitis B virus vaccine among people living with HIV: A meta-analysis

2021

BACKGROUND: There is conflicting evidence about whether a double dose of the hepatitis B virus (HBV) vaccine induces better immunity than the standard-dose vaccine for people living with HIV (PLWH)....

The effects of antidepressant medications on antiretroviral treatment adherence in HIV-positive individuals with depression

2021

Background Extant literature has identified Major Depressive Disorder (MDD) as a comorbid disorder in individuals with seropositive human immunodeficiency disorder (HIV), and this may affect HIV-treatment efficacy. However, there is...

Characteristics and impacts of nutritional programmes to address undernutrition of adults living with HIV in sub-Saharan Africa: A systematic review of evidence

2022

OBJECTIVES: Although some studies have identified various challenges affecting nutritional programmes to effectively tackle undernutrition among people living with HIV, evidence about the characteristics and impacts of these programmes on...

HIV infection and increased risk of COVID-19 mortality: A meta-analysis

2021

There are some concerns on the effect of infection with human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) on the outcome and mortality of COVID-19. In this meta-analysis, we...

Under-nutrition and associated factors among children infected with human immunodeficiency virus in sub-Saharan Africa: A systematic review and meta-analysis

2022

Background In the developing world, such as the sub-Saharan African region, HIV/AIDS has worsened the impact of under-nutrition in children. HIV infected children are highly vulnerable to under-nutrition. Therefore, the...

Decade of research into the acceptability of interventions aimed at improving adolescent and youth health and social outcomes in Africa: A systematic review and evidence map

2021

OBJECTIVE: Interventions aimed at improving adolescent health and social outcomes are more likely to be successful if the young people they target find them acceptable. However, no standard definitions or...

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