Category Archives: Population(s)
The role of targeted HIV screening in the emergency department: A scoping review
BACKGROUND: Human immunodeficiency virus (HIV) infection continues to expand worldwide and a significant proportion of infection is still undiagnosed. Recent studies have addressed the impact and feasibility of ‘opt-out’ HIV...
A systematic review of transfusion-transmissible infections among blood donors and associated safety challenges in Pakistan
The blood transfusion (BT) system in Pakistan is fragmented, demand-driven and depends on weakly regulated transfusion practices. There is a considerable possibility that transfusion-transmissible infections (TTIs) are contributing to the...
Human immunodeficiency virus-related peripheral neuropathy: A systematic review and meta-analysis
Background and purpose: Human immunodeficiency virus (HIV)-associated neurological syndromes occur in affected individuals as a consequence of primary HIV infection, opportunistic infections, inflammation and as an adverse effect of some...
HSV-2 as a biomarker of HIV epidemic potential in female sex workers: Meta-analysis, global epidemiology and implications
This study investigated herpes simplex virus type 2 (HSV-2) seroprevalence utility as a predictor of HIV epidemic potential among female sex workers (FSWs) globally. We updated and analyzed a systematically-assembled...
Adolescent participation in HIV research: Consortium experience in low and middle-income countries and scoping review
Adolescents in low and middle-income countries (LMICs) have a high prevalence of HIV, therefore, it is important that they are included in HIV research. However, ethical challenges regarding consent can...
Comparing the effects of HIV self-testing to standard HIV testing for key populations: A systematic review and meta-analysis
BACKGROUND: We update a previous systematic review to inform new World Health Organization HIV self-testing (HIVST) recommendations. We compared the effects of HIVST to standard HIV testing services to understand...
Rapid evidence review of harm reduction interventions and messaging for people who inject drugs during pandemic events: Implications for the ongoing COVID-19 response
BACKGROUND: People who inject drugs are at increased health risk in a pandemic due to their greater susceptibility to severe disease and as a consequence of the restrictions put in...
Psychosocial support interventions for improved adherence and retention in ART care for young people living with HIV (10-24 years): A scoping review
Background: Mental health disorders such as high levels of anxiety, isolation, depression and suicide ideation reported among young people living with HIV (10-24 years;YPLHIV) contribute significantly to poor medication adherence...
Interactive digital interventions for prevention of sexually transmitted HIV: Systematic review and meta-analyses
BACKGROUND: Digital technology offers good opportunities for HIV prevention. This systematic review assesses the effectiveness of interactive digital interventions (IDIs) for prevention of sexually transmitted HIV. METHODS: We conducted a...
Interventions to improve daily medication use among adolescents and young adults: What can we learn for youth pre-exposure prophylaxis services?
OBJECTIVE: Oral pre-exposure prophylaxis (PrEP) is an important HIV prevention method and studies have shown that young people ages 15-24 have difficulty adhering to daily PrEP. The field of PrEP...
