Category Archives: Population(s)
Clinical relevance of drug interactions in people living with human immunodeficiency virus on antiretroviral therapy—Update 2022: Systematic review
BACKGROUND: The clinical outcomes of antiretroviral drugs may be modified through drug interactions; thus, it is important to update the drug interactions in people living with HIV (PLHIV). AIM: To...
Determining reinfection rates by hepatitis C testing interval among key populations: A systematic review and meta-analysis
Background & aims: Detecting hepatitis C virus (HCV) reinfection among key populations helps prevent ongoing transmission. This systematic review aims to determine the association between different testing intervals during post-SVR follow-up...
SARS-CoV-2 vaccine immunogenicity for people living with HIV: A systematic review and meta-analysis
Background: Previous publications on the immunogenicity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines in people living with HIV (PLWH) have reported inconsistent results. Additionally, a meta-analysis investigating the immunogenicity...
Safety of longer-term doxycycline use: A systematic review and meta-analysis with implications for bacterial sexually transmitted infection chemoprophylaxis
BACKGROUND: Sexually transmitted infections (STIs) such as syphilis, gonorrhea, and chlamydia have significantly increased over the past decade in the United States. Doxycycline as chemoprophylaxis (i.e., postexposure prophylaxis) offers promise...
Can newborn infants with positive HIV soon after birth be diagnosed with intrauterine infection?
BACKGROUND: Mother-to-child transmission (MTCT) of human immunodeficiency virus (HIV) can occur intrauterine, intrapartum, and postpartum. Currently, infants with confirmed positive results in virological tests before 48h of age are defined...
The global prevalence of suicidal ideation and suicide attempts among men who have sex with men: A systematic review and meta-analysis
BACKGROUND: This study aimed to determine the global prevalence of suicidal ideation and attempts among men who have sex with men (MSM) as a systematic review, and meta-analysis. METHODS: For...
Extracorporeal life support for patients with newly diagnosed HIV and acute respiratory distress syndrome: A systematic review and analysis of individual patient data
Extracorporeal membrane oxygenation (ECMO) may improve survival in patients with severe acute respiratory distress syndrome (ARDS). However, presence of immunosuppression is a relative contraindication for ECMO, which is withheld in...
HIV pre-exposure prophylaxis, blood donor deferral, occult infection, and risk of HIV transmission by transfusion: A fine balance between evidence-based donor selection criteria and transfusion safety
Pre- and postexposure prophylaxis for human immunodeficiency virus (HIV) are key to reducing the transmission of this virus. Furthermore, low-toxicity, long-acting formulations provide additional clinical benefits, in particular easier adherence...
A systematic review of interventions for young men who have sex with men and young transgender women living with HIV
Young men who have sex with men (YMSM) and young transgender women (YTGW) have unique challenges to HIV care. We conducted a systematic review to summarize behavioral and structural interventions...
Intervention approaches to address intimate partner violence and HIV: A scoping review of recent research
PURPOSE OF REVIEW: Intimate partner violence (IPV) remains a critical challenge to HIV prevention and treatment efforts across the globe. We examined recently published (January 9, 2017–January 9, 2023) integrated...
Burden of tuberculosis among vulnerable populations worldwide: An overview of systematic reviews
Background Tuberculosis is a communicable disease of public health concern that inequitably impacts the most vulnerable populations worldwide. Vulnerable populations are those with a high risk for tuberculosis disease and...
Oral pre-exposure prophylaxis uptake and acceptability among men who have sex with men: A scoping review of the literature
Despite the global effort to end the human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) epidemic as a global threat by 2030, the rate of new HIV infections worldwide...
