Cost-effectiveness of HIV screening in high-income countries: A systematic review
2018
INTRODUCTION: Over 2 million people in high-income countries live with HIV. Early diagnosis and treatment present benefits for infected subjects and reduce secondary transmissions. Cost-effectiveness analyses are important to effectively...
Evolving models and ongoing challenges for HIV preexposure prophylaxis implementation in the United States
2018
BACKGROUND: The use of preexposure prophylaxis (PrEP) for HIV prevention was approved by the Food and Drug Administration in 2012, but delivery to at-risk persons has lagged. This critical review...
Economic evaluations of pre- and post-exposure prophylaxis for HIV
2019
Key take-home messages Economic evaluations of health care interventions can inform resource allocation and policy development. However, interpreting and generalizing results can be challenging. PrEP can be cost-effective or cost-saving...
Experiences of the HIV cascade of care among indigenous peoples: A systematic review
2019
Indigenous leaders remain concerned that systemic oppression and culturally unsafe care impede Indigenous peoples living with HIV from accessing health services that make up the HIV cascade of care. We...
Sexual abstinence among people living with HIV/AIDS
2011
Key take-home messages Diagnosis of HIV infection can have far-reaching implications: people’s sexual interest, the pleasure they derive from sex, their sense of attractiveness or appeal as a sexual partner...
Adherence to methadone maintenance treatment and antiretroviral therapy
2013
Key take-home messages HIV-positive intravenous drug users (IDUs) are at greater risk of non-adherence to highly active antiretroviral therapy (HAART) compared to the general HIV population. Psychological problems, active drug...
What is the effectiveness of supervised injection services?
2014
Key take-home messages The use of supervised injection services can lead to reductions in injecting behaviour and an increase in the number of clients accessing addiction treatment services. Supervised injection...
Case management and community engagement models
2014
Key take-home messages Very few case management, community capacity building or community development models were found specific to people living with or at-risk of HIV. None were found specific to...
HCV reinfection rates among people who use drugs
2014
Key take-home messages HCV affects people differently. Some are able to spontaneously clear the virus on their own; others develop chronic HCV infection that affects their health and requires treatment....
HIV and STI testing among Indigenous women and women who inject drugs
2016
Key take-home messages Rates of HIV and other sexually transmitted and bloodborne infections are high among Indigenous women and women who inject drugs. For women who use drugs, centres that...
Hepatitis C reinfection after successful treatment
2016
Key take-home messages HCV reinfection rates vary widely. Reinfection depends on the extent to which an individual engages in high risk activities after having achieved sustained virologic response through treatment....
Chest compressions and rescue breathing when administering naloxone in opioid overdose
2016
Key take-home messages Opioid overdoses cause respiratory failure (a reduction or stop in breathing), which can lead to cardiac arrest. In the event of a suspected opioid overdose, bystanders should...
