Adherence to methadone maintenance treatment and antiretroviral therapy
2013
Key take-home messages HIV-positive intravenous drug users (IDUs) are at greater risk of non-adherence to highly active antiretroviral therapy (HAART) compared to the general HIV population. Psychological problems, active drug...
What is the effectiveness of supervised injection services?
2014
Key take-home messages The use of supervised injection services can lead to reductions in injecting behaviour and an increase in the number of clients accessing addiction treatment services. Supervised injection...
Case management and community engagement models
2014
Key take-home messages Very few case management, community capacity building or community development models were found specific to people living with or at-risk of HIV. None were found specific to...
HCV reinfection rates among people who use drugs
2014
Key take-home messages HCV affects people differently. Some are able to spontaneously clear the virus on their own; others develop chronic HCV infection that affects their health and requires treatment....
HIV and STI testing among Indigenous women and women who inject drugs
2016
Key take-home messages Rates of HIV and other sexually transmitted and bloodborne infections are high among Indigenous women and women who inject drugs. For women who use drugs, centres that...
Hepatitis C reinfection after successful treatment
2016
Key take-home messages HCV reinfection rates vary widely. Reinfection depends on the extent to which an individual engages in high risk activities after having achieved sustained virologic response through treatment....
Improving PrEP implementation through multilevel interventions: A synthesis of the literature
2018
There are many challenges to accessing PrEP and thus low uptake in the United States. This review (2007-2017) of PrEP implementation identified barriers to PrEP and interventions to match those...
Predictors of human immunodeficiency virus (HIV) infection in primary care among adults living in developed countries: A systematic review
2018
BACKGROUND: Early diagnosis of human immunodeficiency virus (HIV) is important because antiretroviral therapies are more effective if infected individuals are diagnosed early. Diagnosis of HIV relies on laboratory testing and...
Injection drug use, HIV/HCV, and related services in nonurban areas of the United States: A systematic review
2018
BACKGROUND: Injection drug use (IDU) in nonurban areas of the United States is a growing public health concern, but there has been no comprehensive assessment of existing research on injection-related...
Integrated models of care for individuals with opioid use disorder: How do we prevent HIV and HCV?
2018
PURPOSE OF REVIEW: To describe models of integrated and co-located care for opioid use disorder (OUD), hepatitis C (HCV), and HIV. RECENT FINDINGS: The design and scale-up of multidisciplinary care...
HIV and viral hepatitis among imprisoned key populations
2018
Prisons and other closed facilities create opportunities for transmission of human immunodeficiency virus (HIV) and viral hepatitis during detention and after release. We conducted a systematic review and meta-analysis of...
Health outcomes for clients of needle and syringe programs in prisons
2018
High levels of drug dependence have been observed in the prison population globally, and the sharing of injecting drug equipment in prisons has contributed to higher prevalence of bloodborne diseases...
