Category Archives: People who use drugs

We assessed the association between different levels of needle exchange program (NEP) use and human immunodeficiency virus (HIV) seroconversion in the injecting drug user (IDU) population using meta-analysis to aggregate...

INTRODUCTION: Oral pre-exposure prophylaxis (PrEP) is an effective strategy to reduce the risk of HIV transmission in high risk individuals. However, the effectiveness of oral pre-exposure prophylaxis is highly dependent...

INTRODUCTION: Over 2 million people in high-income countries live with HIV. Early diagnosis and treatment present benefits for infected subjects and reduce secondary transmissions. Cost-effectiveness analyses are important to effectively...

BACKGROUND: The use of preexposure prophylaxis (PrEP) for HIV prevention was approved by the Food and Drug Administration in 2012, but delivery to at-risk persons has lagged. This critical review...

Key take-home messages Economic evaluations of health care interventions can inform resource allocation and policy development. However, interpreting and generalizing results can be challenging. PrEP can be cost-effective or cost-saving...

Key take-home messages Diagnosis of HIV infection can have far-reaching implications: people’s sexual interest, the pleasure they derive from sex, their sense of attractiveness or appeal as a sexual partner...

Key take-home messages HIV-positive intravenous drug users (IDUs) are at greater risk of non-adherence to highly active antiretroviral therapy (HAART) compared to the general HIV population. Psychological problems, active drug...

Key take-home messages The use of supervised injection services can lead to reductions in injecting behaviour and an increase in the number of clients accessing addiction treatment services. Supervised injection...

Key take-home messages Very few case management, community capacity building or community development models were found specific to people living with or at-risk of HIV. None were found specific to...

Key take-home messages HCV affects people differently. Some are able to spontaneously clear the virus on their own; others develop chronic HCV infection that affects their health and requires treatment....

Key take-home messages Rates of HIV and other sexually transmitted and bloodborne infections are high among Indigenous women and women who inject drugs. For women who use drugs, centres that...

Key take-home messages HCV reinfection rates vary widely. Reinfection depends on the extent to which an individual engages in high risk activities after having achieved sustained virologic response through treatment....