Category Archives: General HIV- population
Reviews on HIV- people that explore topics including risk, screening, and prevention
A systematic review of adherence to oral pre-exposure prophylaxis for HIV — How can we improve uptake and adherence?
INTRODUCTION: Oral pre-exposure prophylaxis (PrEP) is an effective strategy to reduce the risk of HIV transmission in high risk individuals. However, the effectiveness of oral pre-exposure prophylaxis is highly dependent...
Paediatric postdischarge mortality in developing countries: A systematic review
OBJECTIVES: To update the current evidence base on paediatric postdischarge mortality (PDM) in developing countries. Secondary objectives included an evaluation of risk factors, timing and location of PDM. DESIGN: Systematic...
Cost-effectiveness of HIV screening in high-income countries: A systematic review
INTRODUCTION: Over 2 million people in high-income countries live with HIV. Early diagnosis and treatment present benefits for infected subjects and reduce secondary transmissions. Cost-effectiveness analyses are important to effectively...
Seroprevalence of HIV among pregnant women in Ethiopia: A systematic review and meta-analysis
OBJECTIVE: This systematic review and meta-analysis aimed to determine the pooled prevalence of HIV among pregnant women in Ethiopia. RESULT: PubMed, EMBASE, Science Direct and Google scholar databases were searched...
A meta-analysis and systematic literature review of factors associated with sexual risk-taking during international travel
BACKGROUND: International travel facilitates global spread of sexually transmitted infections (STI). Travellers could contribute to onward transmission of pathogens rarely encountered at home and export new strains to the destination....
Elimination of HIV transmission through novel and established prevention strategies among people who inject drugs
Despite the effectiveness of existing HIV prevention strategies for people who inject drugs (PWID), uncontrolled outbreaks of HIV among this group are common and occur around the world. In this...
Evolving models and ongoing challenges for HIV preexposure prophylaxis implementation in the United States
BACKGROUND: The use of preexposure prophylaxis (PrEP) for HIV prevention was approved by the Food and Drug Administration in 2012, but delivery to at-risk persons has lagged. This critical review...
The willingness to participate in biomedical research involving human beings in low- and middle-income countries: A systematic review
OBJECTIVES: To systematically review reasons for the willingness to participate in biomedical human subjects research in low- and middle-income countries (LMICs). METHODS: Five databases were systematically searched for articles published...
Economic evaluations of pre- and post-exposure prophylaxis for HIV
Key take-home messages Economic evaluations of health care interventions can inform resource allocation and policy development. However, interpreting and generalizing results can be challenging. PrEP can be cost-effective or cost-saving...
Transmission of drug-resistant tuberculosis in HIV-endemic settings
The emergence and expansion of the multidrug-resistant tuberculosis epidemic is a threat to the global control of tuberculosis. Multidrug-resistant tuberculosis is the result of the selection of resistance-conferring mutations during...
Advances in the understanding of mycobacterium tuberculosis transmission in HIV-endemic settings
Tuberculosis claims more human lives than any other infectious disease. This alarming epidemic has fuelled the development of novel antimicrobials and diagnostics. However, public health interventions that interrupt transmission have...
Effects of migration on risky sexual behavior and HIV acquisition in South Africa: A systematic review and meta-analysis, 2000-2017
While human mobility has been implicated in fueling the HIV epidemic in South Africa, the link between migration and HIV has not been systematically reviewed and quantified. We conducted a...
