Category Archives: Other

Reviews that are lab-based (e.g. genes, pharmaceuticals) or on unique groups of people (e.g. fishermen, nurses)

Polyneuropathy, anti-tuberculosis treatment and the role of pyridoxine in the HIV/AIDS era: A systematic review

2011

Tuberculosis (TB) is increasing in incidence in certain parts of the world, particularly where there is a co-epidemic of human immunodeficiency virus/acquired immune-deficiency syndrome (HIV/AIDS), and it is associated with...

Do prevention interventions reduce HIV risk behaviours among people living with HIV? A meta-analytic review of controlled trials

2006

Objective: To conduct a meta-analytic review of HIV interventions for people living with HIV (PLWH) to determine their overall efficacy in reducing HIV risk behaviours and identify intervention characteristics associated...

Behavioral interventions to reduce HIV-related sexual risk behavior: review and synthesis of meta-analytic evidence

2008

Over the past 25 years, scores of behavioral interventions to reduce HIV-related sexual risk behavior have been developed and evaluated. The purpose of the current study was to synthesize what...

Apricitabine: A nucleoside reverse transcriptase inhibitor for HIV infection

2009

OBJECTIVE: To review the pharmacology, pharmacokinetics, efficacy, and safety of apricitabine, a nucleoside reverse transcriptase inhibitor that is currently under investigation and has fast-track approval status with the Food and...

AIDS in Latin America: Assessing the current status of the epidemic and the ongoing response

2008

Background: This article provides a summary of the current status of the HIV/AIDS epidemic in Latin America, as well as an outline of the diverse responses to it. Methods: A...

Nonnucleoside reverse transcriptase inhibitor resistance and the role of the second-generation agents

2010

OBJECTIVE: To review the current state of nonnucleoside reverse transcriptase inhibitor (NNRTI) resistance, discuss the promising role of second-generation NNRTIs, and provide insight into their clinical utility. DATA SOURCES: Articles...

Interventions to reduce risky sexual behaviour for preventing HIV infection in workers in occupational settings

2011

Background: HIV in the workforce has a negative impact on economic growth and development of affected countries. The workplace provides an important avenue to prevent HIV by providing easy access...

Association between polymorphism of SDF1 (CXCL12) gene and HIV-1 susceptibility: A meta-analysis

2011

Studies on the association between SDF1 genotype and HIV-1 susceptibility have generated inconclusive results. Therefore, we conducted a meta-analysis to summarize the findings of different studies. Articles reporting SDF1 gene...

Role of the inhibitory quotient in HIV therapy

2005

A systemic review is presented of all studies that have evaluated the inhibitory quotient (IQ). The IQ is defined as the ratio between (trough) drug concentration and level of drug...

Modeling the cost-effectiveness of HIV treatment: how to buy the most ‘health’ when resources are limited

2013

PURPOSE OF REVIEW: To summarize recent cost-effectiveness analyses (CEAs) that evaluate optimal treatment strategies for persons living with HIV/AIDS (PLWHA). RECENT FINDINGS: Efforts to attain universal coverage of current treatment...

Treatment non-adherence in pediatric long-term medical conditions: Systematic review and synthesis of qualitative studies of caregivers’ views

2014

BACKGROUND: Non-adherence to prescribed treatments is the primary cause of treatment failure in pediatric long-term conditions. Greater understanding of parents and caregivers’ reasons for non-adherence can help to address this...

Task shifting of HIV management from doctors to nurses in Africa: Clinical outcomes and evidence on nurse self-efficacy and job satisfaction

2013

With 24% global disease burden and 3% global health workforce, the World Health Organization (WHO) designates the African region a critical workforce shortage area. Task shifting is a WHO-recommended strategy...

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