Category Archives: Women
Comorbidities in women living with HIV: A systematic review
Objectives: Effective antiretroviral therapy (ART) has improved the life expectancy of women living with HIV (WLWH). This population is now experiencing age-related comorbidities. This systematic review presents the current understanding of...
HIV testing in termination of pregnancy and colposcopy services: A scoping review
BACKGROUND: Women and girls are relatively under-represented across the HIV treatment cascade. Two conditions unique to women, pregnancy and cervical cancer/dysplasia, share a common acquisition mode with HIV. This scoping...
Safety of tenofovir disoproxil fumarate for pregnant women facing the coronavirus disease 2019 pandemic
We assessed the teratogenicity of tenofovir, a human immunodeficiency virus (HIV) drug similar to remdesivir that is currently being evaluated for the treatment of coronavirus disease 2019 (COVID-19). Using US...
Multi-level interventions to promote oral pre-exposure prophylaxis use among adolescent girls and young women: A review of recent research
PURPOSE OF REVIEW: This review summarizes interventions to promote HIV pre-exposure prophylaxis (PrEP) use among adolescent girls and young women (AGYW) in HIV endemic settings, while also highlighting gaps in...
Mapping evidence on predictors of adverse sexual and reproductive health outcomes among young women in South Africa: A scoping review
BACKGROUND: Globally, most young women have an unmet need for sexual and reproductive health (SRH), which remains a public health concern. Identifying the predictors can help reduce this challenge. AIM:...
Mother-to-child HIV-2 transmission: Comparison with HIV-1 and evaluation of factors influencing the rate of transmission. A systematic review
A review and collection of data on HIV-2 mother-to-child transmission (MTCT) is absent in the literature. This systematic review and meta-analysis aims to provide a pooled estimate of the rate...
HIV test coverage among pregnant women in Ethiopia: A systematic review and meta-analysis
Introduction: A human immunodeficiency virus (HIV) test during pregnancy is the gateway to the prevention of mother-to-child transmission (PMTCT) of HIV. Estimating the national uptake of HIV tests among pregnant...
Sex differences in non-AIDS comorbidities among people with human immunodeficiency virus
Women are grossly underrepresented in human immunodeficiency virus (HIV) clinical and translational research. This is concerning given that people with HIV (PWH) are living longer, and thus accumulating aging-related non-AIDS...
Reproductive justice in the time of COVID-19: A systematic review of the indirect impacts of COVID-19 on sexual and reproductive health
OBJECTIVE: Despite gendered dimensions of COVID-19 becoming increasingly apparent, the impact of COVID-19 and other respiratory epidemics on women and girls’ sexual and reproductive health (SRH) have yet to be...
Systematic review of sex differences in the relationship between hormones and depression in HIV
BACKGROUND: Major depressive disorder is the most common neuropsychiatric comorbidity of human immunodeficiency virus (HIV), and women are more frequently affected in the general population and among those with HIV....
Risk of HIV acquisition among high-risk heterosexuals with nonviral sexually transmitted infections: A systematic review and meta-analysis
BACKGROUND: Nonviral sexually transmitted infections (STIs) increase risk of sexually-acquired HIV infection. Updated risk estimates carefully scrutinizing temporality bias of studies are needed. METHODS: We conducted a systematic review (PROSPERO...
Curable sexually transmitted infections among women with HIV in sub-Saharan Africa: Systematic review and meta-analysis
OBJECTIVES: Sexually transmitted infections (STIs) cause significant morbidity among women with HIV and increase HIV transmission. We estimated the prevalence of four STIs among women with HIV in sub-Saharan Africa...