Category Archives: Treatment

An exploration of group-based HIV/AIDS treatment and care models in Sub-Saharan Africa using a realist evaluation (Intervention-Context-Actor-Mechanism-Outcome) heuristic tool: A systematic review

2017

INTRODUCTION: It is increasingly acknowledged that differentiated care models hold potential to manage large volumes of patients on antiretroviral therapy (ART). Various group-based models of ART service delivery aimed at...

Evidence-based review of statin use in patients with HIV on antiretroviral therapy

2017

INTRODUCTION: As a result of improved safe and effective therapeutic options for human immunodeficiency virus (HIV), life expectancy of those living with HIV is increasing leading to new challenges (e.g.,...

Behavioral interventions targeting alcohol use among people living with HIV/AIDS: A systematic review and meta-analysis

2017

Alcohol use is often reported among people living with HIV/AIDS (PLWHA) and is associated with increased sexual risk and poor medication adherence. This meta-analysis evaluated the efficacy of behavioral interventions...

Systematic review and meta-analysis of secondary prophylaxis for prevention of HIV-related toxoplasmic encephalitis relapse using trimethoprim-sulfamethoxazole

2017

A recent systematic literature and meta-analysis reported relative efficacy of trimethoprim-sulfamethoxazole (TMP-SMX) for the treatment of toxoplasmic encephalitis (TE) in HIV-infected adults. Here, we estimated relapse rates during secondary prophylaxis...

Impact of SMS/GPRS printers in reducing time to early infant diagnosis compared to routine result reporting: A systematic review and meta-analysis

2017

BACKGROUND: Despite significant gains made towards improving access, early infant diagnosis (EID) testing programs suffer from long test turnaround times that result in substantial loss to follow-up and mortality associated...

Harmonizing community-based health worker programs for HIV: A narrative review and analytic framework

2017

BACKGROUND: Many countries have created community-based health worker (CHW) programs for HIV. In most of these countries, several national and non-governmental initiatives have been implemented raising questions of how well...

Transition from paediatric to adult care of adolescents living with HIV in sub-Saharan Africa: Challenges, youth-friendly models, and outcomes

2017

INTRODUCTION: The number of adolescents with perinatally or behaviourally acquired HIV is increasing in low-income countries, and especially in sub-Saharan Africa where HIV prevalence and incidence are the highest. As...

Cross-cultural assessment of HIV-associated cognitive impairment using the Kaufman assessment battery for children: A systematic review

2017

INTRODUCTION: Despite improved efficacy of, and access to, combination antiretroviral therapy (cART), HIV-associated cognitive impairments remain prevalent in both children and adults. Neuropsychological tests that detect such impairment can help...

Micronutrient supplementation in adults with HIV infection

2017

BACKGROUND: Micronutrient deficiencies are common among adults living with HIV disease, particularly in low-income settings where the diet may be low in essential vitamins and minerals. Some micronutrients play critical...

Recent mobile health interventions to support medication adherence among HIV-positive MSM

2017

PURPOSE OF REVIEW: We describe recent mobile health (mHealth) interventions supporting antiretroviral therapy (ART) medication adherence among HIV-positive MSM. RECENT FINDINGS: Keyword searches (1 January 2016-13 May 2017) identified 721...

HIV and the criminalisation of drug use among people who inject drugs: A systematic review

2017

BACKGROUND: Mounting evidence suggests that laws and policies prohibiting illegal drug use could have a central role in shaping health outcomes among people who inject drugs (PWID). To date, no...

Objective impairments of gait and balance in adults living with HIV-1 infection: A systematic review and meta-analysis of observational studies

2017

BACKGROUND: Gait and balance deficits are reported in adults with HIV infection and are associated with reduced quality of life. Current research suggests an increased fall-incidence in this population, with...

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