Category Archives: Treatment
Association between medication regimen complexity and pharmacotherapy adherence: A systematic review
PURPOSE: The purpose of this study was to systematically review evidence regarding the association between regimen complexity and adherence. METHODS: Articles were searched in MEDLINE, LILACS, Cochrane, CINAHL, PsycINFO and...
Scaling a waterfall: A meta-ethnography of adolescent progression through the stages of HIV care in sub-Saharan Africa
INTRODUCTION: Observational studies have shown considerable attrition among adolescents living with HIV across the “cascade” of HIV care in sub-Saharan Africa, leading to higher mortality rates compared to HIV-infected adults...
Health technology-enabled interventions for adherence support and retention in care among US HIV-infected adolescents and young adults: An integrative review
The objective of this integrative review was to describe current US trends for health technology-enabled adherence interventions among behaviorally HIV-infected youth (ages 13-29 years), and present the feasibility and efficacy...
A historical review of HIV prevention and care initiatives in British Columbia, Canada: 1996-2015
INTRODUCTION: British Columbia has made significant progress in the treatment and prevention of HIV since 1996, when Highly Active Antiretroviral Therapy (HAART) became available. However, we currently lack a historical...
Evidence on the cost-effectiveness of lifelong antiretroviral therapy for prevention of mother-to-child transmission of HIV: Implications for resource-limited countries in sub-Saharan Africa
INTRODUCTION: The 2016 World Health Organization (WHO) consolidated guideline recommends lifelong antiretroviral therapy (ART) for all HIV-infected pregnant and breastfeeding women for preventing mother-to-child HIV transmission (PMTCT). Ambiguity remains about...
Determinants of adherence to antiretroviral therapy among HIV-positive adults in sub-Saharan Africa: A systematic review
OBJECTIVE: The rapid scale up of antiretroviral treatment (ART) in sub-Saharan Africa (SSA) has resulted in an increased focus on patient adherence. Non-adherence can lead to drug-resistant HIV caused by...
Clinical and public health implications of acute and early HIV detection and treatment: A scoping review
INTRODUCTION: The unchanged global HIV incidence may be related to ignoring acute HIV infection (AHI). This scoping review examines diagnostic, clinical, and public health implications of identifying and treating persons...
Systematic review and meta-analysis of the adolescent HIV continuum of care in South Africa: the Cresting Wave
CONTEXT: South Africa has the most HIV infections of any country in the world, yet little is known about the adolescent continuum of care from HIV diagnosis through viral suppression....
HIV-free survival at 12-24 months in breastfed infants of HIV-infected women on antiretroviral treatment
OBJECTIVE: To provide estimates of HIV-free survival at 12-24 months in breastfed children by maternal ART (6 months or lifelong) to inform WHO HIV and Infant Feeding guidelines. METHODS: Eighteen...
Global prevalence of hypertension among people living with HIV: A systematic review and meta-analysis
The purpose of this study was to estimate, through meta-analysis, the global prevalence of hypertension among people living with HIV (PLWH). A total of 49 studies published during 2011-2016 with...
