Category Archives: Treatment
An exploration of group-based HIV/AIDS treatment and care models in Sub-Saharan Africa using a realist evaluation (Intervention-Context-Actor-Mechanism-Outcome) heuristic tool: A systematic review
INTRODUCTION: It is increasingly acknowledged that differentiated care models hold potential to manage large volumes of patients on antiretroviral therapy (ART). Various group-based models of ART service delivery aimed at...
Behavioral interventions targeting alcohol use among people living with HIV/AIDS: A systematic review and meta-analysis
Alcohol use is often reported among people living with HIV/AIDS (PLWHA) and is associated with increased sexual risk and poor medication adherence. This meta-analysis evaluated the efficacy of behavioral interventions...
Systematic review and meta-analysis of secondary prophylaxis for prevention of HIV-related toxoplasmic encephalitis relapse using trimethoprim-sulfamethoxazole
A recent systematic literature and meta-analysis reported relative efficacy of trimethoprim-sulfamethoxazole (TMP-SMX) for the treatment of toxoplasmic encephalitis (TE) in HIV-infected adults. Here, we estimated relapse rates during secondary prophylaxis...
Impact of SMS/GPRS printers in reducing time to early infant diagnosis compared to routine result reporting: A systematic review and meta-analysis
BACKGROUND: Despite significant gains made towards improving access, early infant diagnosis (EID) testing programs suffer from long test turnaround times that result in substantial loss to follow-up and mortality associated...
Harmonizing community-based health worker programs for HIV: A narrative review and analytic framework
BACKGROUND: Many countries have created community-based health worker (CHW) programs for HIV. In most of these countries, several national and non-governmental initiatives have been implemented raising questions of how well...
Transition from paediatric to adult care of adolescents living with HIV in sub-Saharan Africa: Challenges, youth-friendly models, and outcomes
INTRODUCTION: The number of adolescents with perinatally or behaviourally acquired HIV is increasing in low-income countries, and especially in sub-Saharan Africa where HIV prevalence and incidence are the highest. As...
Cross-cultural assessment of HIV-associated cognitive impairment using the Kaufman assessment battery for children: A systematic review
INTRODUCTION: Despite improved efficacy of, and access to, combination antiretroviral therapy (cART), HIV-associated cognitive impairments remain prevalent in both children and adults. Neuropsychological tests that detect such impairment can help...
Recent mobile health interventions to support medication adherence among HIV-positive MSM
PURPOSE OF REVIEW: We describe recent mobile health (mHealth) interventions supporting antiretroviral therapy (ART) medication adherence among HIV-positive MSM. RECENT FINDINGS: Keyword searches (1 January 2016-13 May 2017) identified 721...
Objective impairments of gait and balance in adults living with HIV-1 infection: A systematic review and meta-analysis of observational studies
BACKGROUND: Gait and balance deficits are reported in adults with HIV infection and are associated with reduced quality of life. Current research suggests an increased fall-incidence in this population, with...
