Category Archives: Prevention, Engagement and Care Cascade

Traditional male circumcision and the risk for HIV transmission among men: A systematic review

2023

OBJECTIVES: To synthesise evidence to determine whether, in contrast to medical male circumcision, traditional male circumcision (TMC) practices may contribute to HIV transmission and what the impacts of TMC are...

Serological response following COVID-19 vaccines in patients living with HIV: A dose-response meta-analysis

2023

To quantify the pooled rate and risk ratio of seroconversion following the uncomplete, complete, or booster dose of COVID-19 vaccines in patients living with HIV. PubMed, Embase and Cochrane library...

Antivirals for prevention of hepatitis B virus mother-to-child transmission in human immunodeficiency virus positive pregnant women co-infected with hepatitis B virus

2023

BACKGROUND: Hepatitis B virus (HBV)-human Immunodeficiency virus (HIV) co-infection promotes an aggressive disease course of HBV infection. In the only available non-Cochrane systematic review on antiviral therapy during pregnancy for...

Weight and metabolic outcomes in naïve HIV patients treated with integrase inhibitor-based antiretroviral therapy: A systematic review and meta-analysis

2023

Background: The use of integrase inhibitor-based antiretroviral therapy could be associated with worse weight and metabolic outcomes in patients with HIV infection. Methods: PubMed, EMBASE, and Scopus were searched from inception to...

Barriers and facilitators to HIV pre-exposure prophylaxis for cisgender and transgender women in the UK

2023

Uptake of oral HIV pre-exposure prophylaxis (PrEP) among cisgender and transgender women in the UK has been low. In this Review, we explore the barriers and facilitators to PrEP access...

Assessing PrEP messaging and communication: A review of the qualitative literature

2023

Pre-exposure prophylaxis (PrEP) is a biomedical HIV prevention intervention approved by the FDA in 2012. Nevertheless, most sexual minority men (SMM) who could benefit from its use are not currently...

A comprehensive overview on the role of phytocompounds in human immunodeficiency virus treatment

2023

Acquired immune deficiency syndrome (AIDS) is a worldwide epidemic caused by human immunodeficiency virus (HIV) infection. Newer medicines for eliminating the viral reservoir and eradicating the virus are urgently needed....

Methodological and reporting quality of non-inferiority randomised controlled trials comparing antiretroviral therapies: A systematic review

2023

Background: It is unclear whether the reporting quality of antiretroviral non-inferiority randomised controlled trials (ARV NI-RCTs) has improved since the CONSORT guideline release in 2006. The primary objective of this systematic...

HIV prevention intervention-related research with adult, sexual minority hispanic men in the United States: A systematic review

2023

The systematic review describes aims to synthesize the HIV prevention intervention-related research conducted among adult, US sexual minority Hispanic men since 2012. Following PRISMA guidelines, 15 articles representing 14 studies...

Trends in HIV testing, the treatment cascade, and HIV incidence among men who have sex with men in Africa: A systematic review and meta-analysis

2023

Background: Gay, bisexual, and other men who have sex with men (MSM) are disproportionately affected by HIV. In Africa, MSM face structural barriers to HIV prevention and treatment that increase their...

Can peer-based interventions improve adolescent sexual and reproductive health outcomes? An overview of reviews

2023

PURPOSE: An overview of reviews was conducted to summarize the evidence and synthesize the results from systematic reviews. METHODS: The Cochrane and Preferred Reporting Items for Overviews of Reviews reporting...

Implementation and resource needs for long-acting PrEP in low- and middle-income countries: A scoping review

2023

INTRODUCTION: Several low- and middle-income countries (LMICs) are preparing to introduce long-acting pre-exposure prophylaxis (LAP). Amid multiple pre-exposure prophylaxis (PrEP) options and constrained funding, decision-makers could benefit from systematic implementation...

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