Category Archives: Prevention, Engagement and Care Cascade
Interventions connecting young people living in Africa to healthcare; a systematic review using the RE-AIM framework
INTRODUCTION: Africa’s young people are among the least focused groups in healthcare linkage. The disproportionally high burden of youth-related health problems is a burden, especially in developing regions like Africa,...
A community guide systematic review: Digital HIV pre-exposure prophylaxis interventions
INTRODUCTION: HIV preexposure prophylaxis (PrEP) is highly effective when taken as prescribed. Digital health adherence interventions have been identified as effective for improving antiretroviral therapy adherence among people with HIV,...
Interventions, barriers, and facilitators to address the sexual problems of gay, bisexual and other men who have sex with men living with HIV: A rapid scoping review
Sexual problems are common among gay, bisexual, and other men who have sex with men (GBM) after diagnosis with HIV. However, these are often overlooked in care and research, where...
Incidence and risks of HIV infection, medication options, and adverse effects in accidental needle stick injuries: A narrative review
Accidental needle sticks can lead to infections, including HIV. As scientists have learned more about HIV and its replicative physiology, identification of target sites and novel medications have been developed....
High-sensitivity C-reactive protein among people living with HIV on highly active antiretroviral therapy: A systemic review and meta-analysis
The pathological consequences of inflammation persist in people living with the human immunodeficiency virus (PLWH), regardless of the positive outcomes of highly active antiretroviral therapy (HAART). The current systematic review...
Impact of harm minimization interventions on reducing blood-borne infection transmission and some injecting behaviors among people who inject drugs: An overview and evidence gap mapping
Background This study aimed to synthetize the evidence on the effectiveness of harm minimization interventions on reducing blood-borne infection transmission and injecting behaviors among people who inject drugs (PWID) through...
The safety and immunogenicity of vaccines administered to pregnant women living with HIV: A systematic review and meta-analysis
Background Human Immunodeficiency Virus (HIV)-exposed uninfected (HEU) infants have a higher burden of infectious diseases related morbidity and mortality compared with HIV-unexposed uninfected (HUU). Immunization of pregnant women living with...
Effectiveness of linkage to care and prevention interventions following HIV self-testing: A global systematic review and meta-analysis
Over 38.4 million people were living with HIV globally in 2021. The HIV continuum includes HIV testing, diagnosis, linkage to combined antiretroviral therapy (cART), and retention in care. An important...
Endothelial dysfunction, a predictor of cardiovascular disease in HIV patients on antiretroviral therapy: A systematic review and meta-analysis
Aim Although antiretroviral therapy (ART) is available, the rate of new HIV infections is alarming. With this trend, it is anticipated that the use of ART will continue to rise,...
