Category Archives: Prevention, Engagement and Care Cascade

Effectiveness and safety of statins on outcomes in patients with HIV infection: A systematic review and meta-analysis

2022

Statins are hypolipidaemic in human immunodeficiency virus (HIV) positive individuals. However, their effect on all-cause mortality and rate of discontinuation is unclear. We conducted a systematic review to evaluate the...

HIV pre-exposure prophylaxis (PrEP) for transgender and nonbinary persons. Literature review and guidelines for professionals

2022

Transgender and nonbinary (TG/NB) persons are listed as one of the key populations in the context of HIV, due to increased risk of HIV infection in this group. HIV prevention,...

Low-level viraemia: An emerging concern among people living with HIV in Uganda and across sub-Saharan Africa

2022

Attaining viral load (VL) suppression for over 95% of the people living with HIV on antiretroviral therapy is a fundamental step in enabling Uganda and other sub-Saharan African countries to...

Voluntary medical male circumcision for HIV prevention: A global overview

2022

PURPOSE OF REVIEW: With the promise of HIV prevention, there has been a scale-up of voluntary medical male circumcision (VMMC) in high HIV incidence/low circumcision prevalence nations worldwide. Nonetheless, debates...

The proportion of HIV disclosure to sexual partners among people diagnosed with HIV in China: A systematic review and meta-analysis

2022

BACKGROUND: Sexual behavior is one of the main routes of HIV/AIDS spread. HIV disclosure to sexual partners has been confirmed to be an important strategy for HIV/AIDS prevention and control....

Effect of social support interventions on adherence to antiretroviral therapy among people living with HIV: A systematic review and meta-analysis

2022

This systematic review and meta-analysis examined the effects of social support interventions (SSIs) on adherence to antiretroviral therapy (ART) among people living with HIV. We systematically searched Web of Science,...

First line antiretroviral treatment failure and its association with drug substitution and sex among children in Ethiopia: Systematic review and meta-analysis

2022

Antiretroviral Treatment (ART) has significantly decreased HIV-related morbidity and mortality among children despite the issue of drug resistance and subsequent treatment failure appearing as a challenge. Different studies have been...

Antiretroviral drugs for treatment and prevention of HIV infection in adults: 2022 Recommendations of the International Antiviral Society-USA Panel

2023

IMPORTANCE: Recent advances in treatment and prevention of HIV warrant updated recommendations to guide optimal practice. OBJECTIVE: Based on a critical evaluation of new data, to provide clinicians with recommendations...

Barriers and facilitators to the implementation and scale up of differentiated service delivery models for HIV treatment in Africa: A scoping review

2022

BACKGROUND: In the face of health-system constraints, local policymakers and decision-makers face difficult choices about how to implement, expand and institutionalize antiretroviral therapy (ART) services. This scoping review aimed to...

Transition interventions for adolescents on antiretroviral therapy on transfer from pediatric to adult healthcare: A systematic review

2022

Globally, adolescents living with HIV (ALHIV) experience poor health outcomes such as low retention in care, ART non-adherence and viral non-suppression. These outcomes coincide with the period during and after...

Body image in children and adolescents diagnosed with the human immunodeficiency virus: A systematic review

2022

CONTEXT: The relationship with body image, which is the way the body presents itself to each subject, can be aggravated in children and adolescents diagnosed with an human immunodeficiency virus...

Barriers to uptake of long-acting antiretroviral products for treatment and prevention of human immunodeficiency virus (HIV) in high-income countries

2022

Long-acting injectable antiretroviral therapy (LAI-ART) for the treatment and prevention of human immunodeficiency virus (HIV) holds great potential to shift treatment paradigms by offering an alternative to daily oral medication....

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