Category Archives: Biomedical interventions

Prevention strategies for sexually transmitted infections, HIV, and viral hepatitis in Europe

2023

The current prevention efforts for STIs, HIV and viral hepatitis in the WHO European Region, especially in the Central and Eastern subregions, are hindered by healthcare disparities, data gaps, and...

Health facility-based interventions and the uptake of contraception among people living with HIV: A systematic review & meta-analysis

2023

BACKGROUND OBJECTIVES: The prong 2 of 4 prong strategy introduced by the World Health Organization aims at averting unintended pregnancies among people living with HIV (PLHIV). This systematic review aimed...

Adherence, adverse drug reactions, and discontinuation associated with adverse drug reactions of HIV post-exposure prophylaxis: A meta-analysis based on cohort studies

2023

Objective: Evaluate the profiles of post-exposure prophylaxis (PEP) adherence, adverse drug reactions (ADRs), and discontinuation associated with ADRs to provide information for further PEP program improvement and increase adherence to...

A systematic review and meta-analysis of the global prevalence and determinants of COVID-19 vaccine acceptance and uptake in people living with HIV

2023

People living with HIV (PLHIV) are at higher risk of poor outcomes of SARS-CoV-2 infection. Here we report the pooled prevalence of COVID-19 vaccine acceptance/uptake and determinants among this vulnerable...

Awareness, accessibility and uptake of pre-exposure prophylaxis (PrEP) among cisgender and transgender women at risk of HIV infection

2023

Key take-home messages

Effectiveness, uptake and delivery of non-occupational HIV post-exposure prophylaxis (PEP)

2023

Key take-home messages

HPV infection profiles among people living with HIV and HPV vaccine acceptance among individuals with different HIV infection statuses in China: A systematic review and meta-analysis

2023

To understand the HPV infection profiles among Chinese HIV/AIDS patients and the HPV vaccine acceptance among unvaccinated Chinese people with different HIV infection statuses after the HPV vaccine launch in...

Immunogenicity and effectiveness of COVID-19 booster vaccination among people living with HIV: A systematic review and meta-analysis

2023

Background The effect of booster vaccinations with the coronavirus virus disease (COVID-19) vaccine on people living with HIV (PLWH) remains unknown. In this study, we aimed to investigate the immunogenicity...

HIV and mpox: A rapid review

2023

In this review, we discuss the history and epidemiology of mpox, prevention strategies, clinical characteristics and management, severity of mpox among persons with advanced HIV, and areas for future research...

A systematic review of implementation research on determinants and strategies of effective HIV interventions for men who have sex with men in the United States

2023

Men who have sex with men (MSM) are disproportionately affected by HIV, accounting for two-thirds of Men who have sex with men (MSM) are disproportionately affected by HIV, accounting for...

SARS-CoV-2 vaccine immunogenicity for people living with HIV: A systematic review and meta-analysis

2023

Background: Previous publications on the immunogenicity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines in people living with HIV (PLWH) have reported inconsistent results. Additionally, a meta-analysis investigating the immunogenicity...

Safety of longer-term doxycycline use: A systematic review and meta-analysis with implications for bacterial sexually transmitted infection chemoprophylaxis

2023

BACKGROUND: Sexually transmitted infections (STIs) such as syphilis, gonorrhea, and chlamydia have significantly increased over the past decade in the United States. Doxycycline as chemoprophylaxis (i.e., postexposure prophylaxis) offers promise...

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