Category Archives: Health Systems

Systematic review of interventions aimed at improving HIV adherence to care in low- and middle-income countries in Sub-Saharan Africa

2022

Long-term adherence to antiretroviral medication continues to present as a challenge along the continuum of the HIV care cascade. HIV interventions and support programs are significantly threatened in resource-limited settings...

Safety and efficacy of abacavir for treating infants, children, and adolescents living with HIV: A systematic review and meta-analysis

2022

Background: Abacavir is a nucleoside reverse transcriptase inhibitor recommended in paediatric HIV care. We assessed the safety and efficacy profile of abacavir used in first, second, or subsequent lines of treatment...

Narrative review of studies on HIV pre-exposure prophylaxis in Brazil and its implementation in the public health network

2022

OBJECTIVES: To discuss studies conducted in Brazil relating to PrEP, from 2012 to 2022, based on a narrative review. METHODOLOGY: The databases of the Virtual Health Library/PAHO, portals from Scielo,...

Ingestible electronic sensors for monitoring real-time adherence to HIV pre-exposure prophylaxis and antiretroviral therapy

2022

PURPOSE OF REVIEW: This review summarizes the recent advancements and future directions of digital pill systems (DPS) – which utilize ingestible sensors to directly measure medication ingestion events in real-time...

Determinants of voluntary counseling and testing service uptake among adult sub-Saharan Africans: A systematic review and meta-analysis

2022

Objective: To examine the major determinants of VCT service uptake among adults in SSA. Methods: Electronic databases were searched to identify eligible English language publications. Reporting of the study selection...

Mathematical models for evaluating effectiveness and cost-effectiveness of cervical cancer control policies in populations including women living with human immunodeficiency virus: A scoping review

2022

Objectives: Mathematical modeling is increasingly used to inform cervical cancer control policies, and model-based evaluations of such policies in women living with human immunodeficiency virus (HIV) are an emerging research area....

The clinical effect of point-of-care HIV diagnosis in infants: A systematic review and meta-analysis

2022

Background: Timely diagnosis and treatment of HIV is crucial in HIV-exposed infants to prevent the high rates of mortality seen during the first 2 years of life if HIV is untreated....

Economic benefits of the United States’ AIDS drug assistance program: A systematic review of cost analyses to guide research and policy priorities

2022

As part of the Ryan White HIV/AIDs Program, the federally-funded, state-administered AIDS Drug Assistance Program (ADAP) provides prescription drug medications, including antiretroviral therapy, for people with HIV (PWH) who are...

Evaluating the impact of the COVID-19 pandemic on accessing HIV services in South Africa: A systematic review

2022

Progress has been made towards controlling the Human Immunodeficiency Virus (HIV) epidemic in South Africa. However, the emergence of coronavirus disease 2019 (COVID-19) has disrupted access to health care. This...

HIV-specific patient-reported outcome measures: A systematic review of [sychometric properties

2022

BACKGROUND: The management of people living with HIV/AIDS (PLWHA) is multidimensional and complex. Using patient-reported outcome measures (PROMs) has been increasingly recognized to be the key factor for providing patient-centered...

Rethinking mental health wellness among adolescents living with HIV in the African context: An integrative review of mental wellness components

2022

OBJECTIVE: Adolescents living with HIV (ALHIV) are considered to be at heightened risk for developing mental health problems in comparison to their peers due to the burden of living with...

Provision of HIV pre-exposure prophylaxis to female patients seeking family planning services in the United States

2022

OBJECTIVE: We conducted a scoping review to assess barriers to and facilitators of integrating HIV pre-exposure prophylaxis (PrEP) and family planning (FP) at the patient, provider, and implementation levels, and...

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