SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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The effect of HIV/AIDS infection on the clinical outcomes of COVID-19: A meta-analysis

2022

PURPOSE: Patients with HIV may be more likely to become severely ill from COVID-19. The present meta-analysis aims to determine the impact of HIV/AIDS infection on the clinical outcomes of...

Prevalence, socio-demographics and service use determinants associated with disclosure of HIV/AIDS status to infected children: A systematic review and meta-analysis by 1985–2021

2022

Background Human immunodeficiency virus (HIV)/Acquired Immune Deficiency Syndrome (AIDS) is a public health issue of global importance. To our knowledge, no previous meta-analysis documenting the prevalence, socio-demographic, and service use...

Benefits and risks of rapid initiation of antiretroviral therapy: A systematic review and meta-analysis

2022

Objectives: To compare the benefits and risks between Rapid ART and standard/delayed treatment for HIV. Methods: Databases of PubMed, Cochrane Library, Embase and Web of science were searched from the inception to...

Hepatitis C virus coinfection in people with human immunodeficiency cirus in Iran: A systematic review and meta-analysis

2022

Background: Hepatitis C virus (HCV) coinfection is associated with higher mortality and morbidity in people with human immunodeficiency virus (PWH). Methods: We aimed to characterize the epidemiology and factors associated with HCV...

Chronic disease care integration into primary care services in sub-Saharan Africa: A ‘best fit’ framework synthesis and new conceptual model

2022

OBJECTIVE: To examine the relevance of existing chronic care models to the integration of chronic disease care into primary care services in sub-Saharan Africa and determine whether additional context-specific model...

Measuring and addressing stigma within HIV interventions for people who use drugs: A scoping review of recent research

2022

PURPOSE OF REVIEW: Persistent stigma remains a crucial barrier to HIV prevention and treatment services among people who use drugs (PWUD), particularly for those living with or at-risk for HIV....

What is polypharmacy in people living with HIV/AIDS? A systematic review

2022

Polypharmacy in people living with HIV/AIDS (PLWHA) is a rising morbidity that exacts hefty economic burden on health budgets in addition to other adverse clinical outcomes. Despite recent advances, uncertainty...

Barriers and facilitators to primary care engagement for people who inject drugs: A systematic review

2022

INTRODUCTION: People who inject drugs (PWID) have a greater burden of multimorbid chronic diseases than the general population. However, little attention has been paid to the engagement in primary care...

Voluntary medical male circumcision for HIV prevention: A global overview

2022

PURPOSE OF REVIEW: With the promise of HIV prevention, there has been a scale-up of voluntary medical male circumcision (VMMC) in high HIV incidence/low circumcision prevalence nations worldwide. Nonetheless, debates...

The use of electronic medical records to prompt HIV testing

2022

Key take-home message Canada has met The Joint United Nations Programme on HIV/AIDS (UNAIDS) goal of testing 90% of all people living with HIV; however, an estimated 6,950 people living...

Risk of HIV acquisition among high-risk heterosexuals with nonviral sexually transmitted infections: A systematic review and meta-analysis

2022

BACKGROUND: Nonviral sexually transmitted infections (STIs) increase risk of sexually-acquired HIV infection. Updated risk estimates carefully scrutinizing temporality bias of studies are needed. METHODS: We conducted a systematic review (PROSPERO...

Systematic review and meta-analyses of the interaction between HIV infection and COVID-19: Two years’ evidence summary

2022

Introduction During the COVID-19 pandemic, people living with HIV (PLWH) were considered to be at risk of worse COVID-19 outcomes once infected. However, the existing evidence is inconsistent. This systematic...

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