SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Traditional Chinese medicine for HIV-associated acute herpes zoster: A systematic review and meta-analysis of randomized trials

2022

Background: Herpes zoster (HZ) is a common infection in individuals with acquired immunodeficiency syndrome (AIDS) patients. Traditional Chinese medicine (TCM) has been used widely in clinical practice for HZ, which remains...

HIV serostatus disclosure and its predictors among children living with HIV in Ethiopia: A systematic review and meta-analysis

2022

Background HIV disclosure among children refers to when the caregiver is having disclosed to the child that he or she has HIV specifically. Disclosure significantly improved adherence to treatment and...

Meta-synthesis and science mapping analysis of HIV/HPV co-infection: A global perspective with emphasis on Africa

2022

BACKGROUND: Viral infections are emerging with diverse clinical relevance both in endemic environments and non-endemic regions of the world. Some of the viruses cause co-infections that are of public health...

Best practices to increase the uptake of HIV and HCV testing among people who use drugs

2022

Interventions that provide HIV and/or HCV testing have been offered in a variety of settings. These include community settings such as outpatient drug treatment clinics, mobile clinics, harm reduction services...

The effect of antiretroviral therapy with high central nervous system penetration on HIV-related cognitive impairment: A systematic review and meta-analysis

2022

Chronic complications are a significant concern for people living with HIV/AIDS (PLWHA) infection. HIV-associated neurocognitive disorders (HAND) are prevalent in PLWHA. Yet, the efficacy of medications that penetrate the central...

The “4th 90” target as a strategy to improve health-related quality of life of people living with HIV in sub-Saharan Africa

2022

OBJECTIVES: Next to monitoring the clinical health of people living with HIV through the triple 90 targets, a 4th 90 target was proposed in 2016 to improve HIV health-related quality...

Neuroinflammation in HIV-associated depression: Evidence and future perspectives

2022

People living with HIV face a high risk of mental illness, especially depression. We do not yet know the precise neurobiological mechanisms underlying HIV-associated depression. Depression severity in the general...

Diagnostic accuracy of cervical cancer screening strategies for high-grade cervical intraepithelial neoplasia (CIN2+/CIN3+) among women living with HIV: A systematic review and meta-analysis

2022

BACKGROUND: We systematically reviewed the diagnostic accuracy of cervical cancer screening and triage strategies in women living with HIV (WLHIV). METHODS: Cochrane Library, Embase, Global Health and Medline were searched...

Systematic review of interventions aimed at improving HIV adherence to care in low- and middle-income countries in Sub-Saharan Africa

2022

Long-term adherence to antiretroviral medication continues to present as a challenge along the continuum of the HIV care cascade. HIV interventions and support programs are significantly threatened in resource-limited settings...

Sexual and reproductive health services during outbreaks, epidemics, and pandemics in sub-Saharan Africa: A literature scoping review

2022

BACKGROUND: The COVID-19 pandemic could worsen adolescent sexual and reproductive health (ASRH). We sought evidence on the indirect impacts of previous infectious disease epidemics and the current COVID-19 pandemic on...

Does voluntary medical male circumcision reduce HIV risk in men who have sex with men?

2022

PURPOSE OF REVIEW: To review the evidence on the effect of voluntary medical male circumcision (VMMC) on reducing HIV risk among men who have sex with men (MSM) and assess...

A systematic review of four decades of prevalence of oral soft tissue infections and conditions among adult HIV patients in India

2022

Oral lesions are a cue for decreased immunity among Human Immunodeficiency Virus (HIV) positive patients. There is no cumulative data available related to the prevalence of oral soft tissue lesions...

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