SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Does HIV infection affect the survival of dental implants? A systematic review and meta-analysis

2021

STATEMENT OF PROBLEM: Immunosuppression and coinfections associated with human immunodeficiency virus (HIV) infection pose a relative contraindication for dental implant therapy. However, although implants have been placed in patients with...

Best practices of same-day HIV pre-exposure prophylaxis (PrEP) initiation

2021

Several clinics have implemented same-day PrEP programs and have reported that clinics offering this model of care, in general, have positive health outcomes. Studies also report that same-day PrEP is...

Decade of research into the acceptability of interventions aimed at improving adolescent and youth health and social outcomes in Africa: A systematic review and evidence map

2021

OBJECTIVE: Interventions aimed at improving adolescent health and social outcomes are more likely to be successful if the young people they target find them acceptable. However, no standard definitions or...

Clinical progression of COVID-19 coinfection in people living with the human immunodeficiency virus: Scoping review

2021

OBJECTIVES: to map the production of scientific knowledge on the clinical progression of COVID-19 coinfection in people living with the human immunodeficiency virus (HIV). METHODS: scoping review, with search strategies...

TLR-agonist mediated enhancement of antibody-dependent effector functions as strategy for an HIV-1 cure

2021

BACKGROUND: The current treatment for HIV-1 is based on blocking various stages in the viral replication cycle using combination antiretroviral therapy (ART). Even though ART effectively controls the infection, it...

Strategies to reengage patients lost to follow up in HIV care in high income countries, a scoping review

2021

BACKGROUND: Despite remarkable achievements in antiretroviral therapy (ART), losses to follow-up (LTFU) might prevent the long-term success of HIV treatment and might delay the achievement of the 90-90-90 objectives. This...

Differences in outcomes of chemoradiation in women with invasive cervical cancer by human immunodeficiency virus status: A systematic review

2021

PURPOSE: Cervical cancer is one of the leading causes of cancer death among women worldwide, and women living with human immunodeficiency virus (HIV) carry the highest burden of disease. Chemoradiation...

HIV infection and multidrug resistant tuberculosis: a systematic review and meta-analysis

2021

BACKGROUND: Multidrug-resistant tuberculosis (MDR-TB) in HIV infected individuals is a serious threat to global efforts to combat tuberculosis. Inconsistent findings on the association between HIV infection and MDR-TB were present...

Health and Health Care Access Barriers Among Transgender Women Engaged in Sex Work: A Synthesis of U.S.-Based Studies Published 2005-2019

2021

Purpose: Transgender women (TW) are likely to experience job discrimination and engage in commercial sex transactions. As a group, they have the highest risk for HIV/AIDS. However, little is known...

Neurotoxicities in the treatment of HIV between dolutegravir, rilpivirine and dolutegravir/rilpivirine: A meta-analysis

2021

Objective: To assess the risk of neuropsychiatric adverse effects (ie, depression, anxiety, insomnia, dizziness, suicidal behaviour) among patients treated with rilpivirine, dolutegravir and dolutegravir/rilpivirine. Design: This is a systematic review and meta-analysis of...

Assessing the costs and outcomes of control programmes for sexually transmitted infections: A systematic review of economic evaluations

2021

OBJECTIVE: To identify economic evaluations of interventions to control STIs and HIV targeting young people, and to assess how costs and outcomes are measured in these studies. DESIGN: Systematic review....

Antiretroviral therapy and detection of high-grade cervical intraepithelial neoplasia (CIN2+) at post-CIN management follow-up among women living with human immunodeficiency virus: A systematic review and meta-analysis

2021

Background: We evaluated the association of antiretroviral therapy (ART), CD4+ count and human immunodeficiency virus (HIV) plasma viral load (PVL) on high-grade cervical intraepithelial neoplasia (CIN2+) detection at follow-up after CIN...

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