SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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The willingness to participate in biomedical research involving human beings in low- and middle-income countries: A systematic review

2019

OBJECTIVES: To systematically review reasons for the willingness to participate in biomedical human subjects research in low- and middle-income countries (LMICs). METHODS: Five databases were systematically searched for articles published...

Neurocysticercosis and HIV Infection: What can we learn from the published literature?

2019

OBJECTIVE: Infections caused by the human immunodeficiency virus (HIV) and by the larvae of Taenia solium (i.e., cysticercosis) are still widespread in many developing countries. Both pathologies modify host immune...

Depression and HIV disease progression: A mini-review

2019

Background: Depression is the most common mental disorder and a leading cause of disability, which commonly presents unexplained psychological and physical symptoms. Depression and HIV/AIDS are commonly comorbid. This review...

Cancer disparities in people with HIV: A systematic review of screening for non-AIDS-defining malignancies

2019

BACKGROUND: People with HIV (PWHIV) have improved survival because of the advent of antiretroviral therapy. Consequently, PWHIV experience higher rates of non-acquired immunodeficiency syndrome-defining malignancies (NADMs). Previous studies have demonstrated...

Cost of differentiated HIV antiretroviral therapy delivery strategies in sub-Saharan Africa: A systematic review

2019

BACKGROUND: Efficient and scalable models for HIV treatment are needed to maximize health outcomes with available resources. By adapting services to client needs, differentiated antiretroviral therapy (DART) has the potential...

HIV prevalence among tuberculosis patients in sub-Saharan Africa: A systematic review and meta-analysis

2019

HIV associated tuberculosis (TB) morbidity and mortality is a major concern in sub-Saharan Africa. Understanding the level of HIV infection among TB patients is vital for adequate response. We conducted...

Human immunodeficiency virus and risk of pre-eclampsia and eclampsia in pregnant women: A meta-analysis on cohort studies

2019

Maternal HIV infection is related to several perinatal adverse outcomes. This study is aimed at establishing whether maternal HIV infection is associated with the development of pre-eclampsia (PE) and eclampsia....

Difference in Toxoplasma gondii seroprevalence rates due to low and high CD4 counts in patients with HIV/AIDS

2019

Objective: Since symptomatic toxoplasmosis in in human immunodeficiency virus (HIV)/Acquired immunodeficiency syndrome (AIDS) almost always occurs as a result of reactivation of chronic infection, screening Toxoplasma serology has an important...

HIV pre-exposure prophylaxis (PrEP) awareness and acceptability among trans women: a review

2019

Transgender (trans) women are disproportionally burdened by the HIV epidemic due to complex structural, psychosocial and biological factors. HIV pre-exposure prophylaxis (PrEP) is a biomedical prevention approach for people at...

Safety and immunogenicity of measles vaccination in HIV-infected and HIV-exposed uninfected children: A systematic review and meta-analysis

2019

Background: HIV-infected and HIV-exposed uninfected (HEU) children have an increased risk of measles that may be due to altered immune responses or suboptimal timing of measles vaccination. We aimed to...

The efficacy of post-exposure prophylaxis (PEP) for HIV

2019

Key take-home messages PEP initiated soon after exposure can reduce the risk of HIV seroconversion after occupational and non-occupational exposures, provided adherence to medications is sufficient. Evidence suggests that individuals...

Preventing sexually transmitted and blood borne infections (STBBIs) among sex workers: A critical review of the evidence on determinants and interventions in high-income countries

2019

BACKGROUND: Across diverse regions globally, sex workers continue to face a disproportionate burden of HIV and other sexually transmitted and blood borne infections (STBBIs). Evidence suggests that behavioural and biomedical...

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