SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Employment support services for LGBTQ+ individuals

2018

Key take-home messages Discrimination creates a significant barrier for LGBTQ+ individuals in many stages of their career development. Experiences of discrimination in the workplace differ between LGBTQ+ individuals and are...

The impact of approaches in improving male partner involvement in the prevention of mother-to-child transmission of HIV on the uptake of safe infant feeding practices by HIV positive women in sub-Saharan Africa. A systematic review and meta-analysis

2018

BACKGROUND: The low level of male partner involvement in Prevention of Mother to Child Transmission of HIV services such as safe infant feeding practices poses a serious challenge to the...

The effectiveness and cost-effectiveness of screening for HIV in migrants in the EU/EEA: A systematic review

2018

Migrants, defined as individuals who move from their country of origin to another, account for 40% of newly-diagnosed cases of human immunodeficiency virus (HIV) in the European Union/European Economic Area...

The twin epidemics: Prevalence of TB/HIV co-infection and its associated factors in Ethiopia; A systematic review and meta-analysis

2018

BACKGROUND: Tuberculosis and HIV/AIDS are the major public health problems in many parts of the world particularly in resource limited countries like Ethiopia. Although studies have been conducted on the...

Injection drug use, HIV/HCV, and related services in nonurban areas of the United States: A systematic review

2018

BACKGROUND: Injection drug use (IDU) in nonurban areas of the United States is a growing public health concern, but there has been no comprehensive assessment of existing research on injection-related...

Repurposing medications for use in treating HIV infection: A focus on valproic acid as a latency-reversing agent

2018

WHAT IS KNOWN AND OBJECTIVE: Combined antiretroviral therapy (ART) reduces human immunodeficiency virus type 1 (HIV-1) RNA plasma levels below the limit of detection. However, HIV-1 persists in latently infected...

Age-specific global prevalence of hepatitis B, hepatitis C, HIV, and tuberculosis among incarcerated people: A systematic review

2018

PURPOSE: This study aims to compare the global prevalence of hepatitis B, hepatitis C, HIV, and tuberculosis in incarcerated adolescents and young adults (AYAs) and older prisoners. METHODS: This study...

Interleukin gene polymorphisms and susceptibility to HIV-1 infection: A meta-analysis

2018

Some subjects are repeatedly exposed to human immunodeficiency virus (HIV), yet they remain uninfected. This suggests the existence of host-resistance mechanisms. The current study synthesizes the evidence regarding the association...

Neurodevelopment in young children born to HIV-infected mothers: A meta-analysis

2018

CONTEXT: HIV-infected (HIV+) children have worse neurodevelopmental outcomes compared with HIV-uninfected children. However, little is known regarding the differences in neurodevelopment between young HIV+ children, HIV-exposed but uninfected (HEU) children,...

The CCR5-Delta32 genetic polymorphism and HIV-1 infection susceptibility: A meta-analysis

2018

The CC chemokine receptor 5 (CCR5) is a chemokine receptor which is widely expressed in several immune cells involved in the inflammatory responses. Previous published studies revealed the relation of...

Tuberculosis-human immunodeficiency virus (HIV) co-infection in Ethiopia: A systematic review and meta-analysis

2018

BACKGROUND: Human Immunodeficiency Virus (HIV) and Tuberculosis (TB) are the double burden diseases of the world. The African continent takes a great share of TB-HIV cases worldwide. This study was...

Assessing the efficacy of lopinavir/ritonavir-based preferred and alternative second-line regimens in HIV-infected patients: A meta-analysis of key evidence to support WHO recommendations

2018

Background: Nucleoside reverse transcriptase inhibitors (NRTIs) and non-NRTIs (NNRTIs) with boosted protease inhibitors are included in standardized first-line and second-line regimens. Recent World Health Organization (WHO) guidelines recommend a boosted...

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