SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Acquired epidermodysplasia verruciformis syndrome in HIV-infected patients: A systematic review

2024

Congenital epidermodysplasia verruciformis (CEV) is a Genodermatosis linked to different inheritance patterns and mutations of the EVER1/TMC6 and EVER2/TMC8 genes. There is an acquired form (AEV) associated with immunodeficiency states,...

Global, regional, and national prevalence of HIV-1 drug resistance in treatment-naive and treatment-experienced children and adolescents: A systematic review and meta-analysis

2024

Background Despite significant reductions in mother-to-child HIV-1 transmission risks due to the advancements and scale-up of antiretroviral therapy (ART), the global burden of HIV-1 drug resistance (HIVDR) in treatment-naive and...

From conceptualising to modelling structural determinants and interventions in HIV transmission dynamics models: A scoping review and methodological framework for evidence-based analyses

2024

Background Including structural determinants (e.g. criminalisation, stigma, inequitable gender norms) in dynamic HIV transmission models is important to help quantify their population-level impacts and guide implementation of effective interventions that...

Barriers and facilitators of physical activity in people living with HIV: A systematic review of qualitative studies

2024

BACKGROUND: Most people living with HIV (PLWH) are sedentary. This study aimed to synthesize the findings of qualitative studies to understand barriers and facilitators of physical activity (PA) among PLWH,...

How does intersectionality impact the quality of healthcare services for Black women living with HIV?

2024

Women with HIV are affected more than men by intersecting discriminations. For Black women, additional discrimination can have a detrimental effect on their HIV care. An extended literature review of...

HIV interventions across the care continuum for adolescents in high-burden countries: A systematic review and meta-analysis

2024

BACKGROUND: Adolescents (10-19 years old) have poor outcomes across the prevention-to-treatment HIV care continuum, leading to significant mortality and morbidity. We conducted a systematic review and meta-analysis of interventions that...

Linkage to care and prevention after HIV self-testing: A systematic review and meta-analysis

2024

INTRODUCTION: Effective linkage to prevention and care is a crucial step following HIV testing services. This systematic review aimed to determine the proportion of individuals linked to prevention and care...

Sexual and reproductive health and rights, HIV and migration in southern Africa: A rapid review

2024

Migration, a prevalent global phenomenon, significantly impacts health, particularly in low- to middle-income countries. This article presents a rapid review aimed at mapping projects, lessons and policies concerning sexual and...

Cardio-metabolic health of offspring exposed in utero to human immuno-deficiency virus and anti-retroviral treatment: A systematic review

2024

BACKGROUND: Antiretroviral treatment (ART) use during pregnancy continues to rise as it is known to decrease the likelihood of HIV transmission from mother to child. However, it is still unknown...

Mental health burden among females living with HIV and AIDS in sub-Saharan Africa: A systematic review

2024

Mental health problems, particularly depression and anxiety, are common in women and young girls living with HIV/ AIDS particularly in low- and middle-income (LMICs) countries where women’s vulnerability to psychiatric...

Association of vitamin D with HIV infected individuals, TB infected individuals, and HIV-TB co-infected individuals: A systematic review and meta-analysis

2024

Background Vitamin D deficiency (VDD) is a worldwide disease. VDD is also associated with an increased risk of HIV-related comorbidities and mortality, and patients have a tendency to develop active...

Weight gain, obesity, and the impact of lifestyle factors among people living with HIV: A systematic review

2024

HIV remains a significant health concern, but the advent of antiretroviral therapy (ART) has transformed it into a manageable chronic condition. However, weight gain and obesity pose a substantial challenge...

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