SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Differential genotypic evolution of HIV-1 quasispecies in cerebrospinal fluid and plasma: A systematic review

2013

HIV-1 enters the central nervous system by passing the blood-brain barrier during primary infection. Despite the introduction of combination antiretroviral therapy, the prevalence of HIV-associated neurocognitive disorders remains high and...

Integration of family planning into HIV services: A synthesis of recent evidence

2013

INTRODUCTION: Increasing access to contraception among women who enter the health system for HIV care is crucial to help them achieve their fertility intentions and reduce vertical transmission of HIV....

HIV transmission from husbands to wives in Cambodia: A systematic review of the literature

2013

HIV transmission in Cambodia has declined considerably in recent years, yet new incidents of HIV transmission within marital relationships have increased. Evidence suggests that the cause of this is transmission...

Effects of postnatal interventions for the reduction of vertical HIV transmission on infant growth and non-HIV infections: A systematic review

2013

INTRODUCTION: Guidelines in resource-poor settings have progressively included interventions to reduce postnatal HIV transmission through breast milk. In addition to HIV-free survival, infant growth and non-HIV infections should be considered....

Workplace programmes for HIV and tuberculosis: A systematic review to support development of international guidelines for the health workforce

2013

The health service sector has a vital role to play in delivering human immunodeficiency virus (HIV) and tuberculosis (TB) prevention, treatment and care, yet evidence indicates that healthcare workers (HCWs)...

High mortality amongst adolescents and adults with bacterial meningitis in sub-Saharan Africa: An analysis of 715 cases from Malawi

2013

Mortality from bacterial meningitis in African adults is significantly higher than those in better resourced settings and adjunctive therapeutic interventions such as dexamethasone and glycerol have been shown to be...

Interventions for the prevention of mycobacterium avium complex in adults and children with HIV

2013

BACKGROUND: Mycobacterium avium complex (MAC) infection is a common complication of advanced acquired immunodeficiency syndrome (AIDS) disease and is an independent predictor of mortality and shortened survival. OBJECTIVES: To determine...

Meta-analyses of fertility desires of people living with HIV

2013

BACKGROUND: Literature review has shown that some years back the fertility desires of people living with HIV was low but in the recent years, it was reported as increasing. However,...

Clinical utility of biomarkers of endothelial activation and coagulation for prognosis in HIV infection: A systematic review

2013

INTRODUCTION: HIV infection is associated with vascular dysfunction and adverse cardiovascular outcomes. Our objective was to review the evidence regarding the clinical utility of endothelial activation and coagulation biomarkers for...

Rapid point-of-care HIV testing in youth: A systematic review

2013

PURPOSE: This review examines the literature surrounding acceptability of, and preference for, rapid point-of-care (POC) human immunodeficiency virus (HIV) testing in youth, documents notification rates when youth were offered rapid...

The age of initiation of drug use and sexual behavior may influence subsequent HIV risk behavior: A systematic review.

2013

Researchers examining injection drug users (IDUs) in drug treatment have been trying for decades to determine the optimal way to intervene to prevent the transmission and spread of human immunodeficiency...

Association between regulated upon activation, normal T cells expressed and secreted (RANTES) -28C/G polymorphism and susceptibility to HIV-1 infection: A meta-analysis

2013

BACKGROUND: Many studies have investigated the distributions of RANTES genotypes between HIV-1 infected patients and uninfected individuals. However, no definite results have been put forward about whether the RANTES -28C/G...

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