SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Systematic review of sexual violence against sex workers: Implications for mental and sexual health

2026

Background: Sex workers worldwide experience different forms of violence and stigma that increase the risk of adverse health outcomes. It is assumed that a discriminatory, criminalizing context as well as intersectional...

Family-centred care for children and adolescents living with HIV in sub-Saharan Africa: A scoping review

2026

Introduction Children and adolescents living with HIV in sub-Saharan Africa (SSA) continue to face significant barriers to diagnosis, treatment adherence, retention in care and psychosocial support, despite progress in prevention...

Integrating smoking cessation into HIV care settings: A systematic review and meta-analysis of effectiveness and the evidence gap in cost-effectiveness

2026

The prevalence of smoking among people living with HIV (PLWH) is higher than in the general population, and PLWH who smoke are at increased risk of both smoking- and HIV-related...

Can ChatGPT match physicians in the diagnosis, triage, management and prevention of infectious diseases? A scoping review

2026

INTRODUCTION: The global burden of infectious diseases (ID), combined with a shortage of ID specialists, continues to challenge healthcare systems worldwide. Artificial intelligence (AI), particularly large language models such as...

Incidence and predictors of opportunistic infection among people living with HIV in Ethiopia: A systematic review and meta-analysis

2026

Background Opportunistic infections (OIs) play a crucial role in the morbidity and mortality of HIV‐infected individuals. Despite the increasing use of antiretroviral therapy, there remains a lack of comprehensive data...

Harm reduction progams and interventions for equity-deserving populations who use crack-cocaine. A scoping review

2026

BACKGROUND: Crack-cocaine use is associated with severe physical and mental health consequences, including cardiac, pulmonary and psychiatric conditions. It also heightens the risk of overdose and transmission of infectious diseases...

Efficacy of long-acting injectable cabotegravir and rilpivirine compared with daily oral antiretroviral therapy in patients with HIV: A systematic review

2026

Long-acting antiretroviral therapy (ART) has emerged as an innovative strategy to address limitations associated with daily oral regimens in people living with human immunodeficiency virus type 1 (HIV-1), including adherence...

Cardiovascular diseases among people living with HIV/AIDS in Ethiopia: A scoping review

2026

Background Human Immunodeficiency Virus (HIV)/ Acquired Immunodeficiency Syndrome (AIDS) remains a significant burden in Ethiopia. People living with HIV/AIDS (PLWHA) are at increased risk of cardiovascular diseases due to both...

Associations between depressive symptoms and memory functions in persons with HIV: A systematic review and meta-analysis

2026

Episodic memory impairment can persist in persons with HIV (PWH) despite treatment. Depression is among the most prevalent comorbidities in HIV. Changes to brain regions involved in episodic memory like...

Perspective of people living with HIV and healthcare workers on the uptake, barriers, and benefits of multimonth dispensing: A qualitative systematic review

2026

INTRODUCTION: Multimonth dispensing (MMD) is a strategy in the HIV care continuum for people living with HIV (PLWH), especially for those who are virally suppressed. With the increase in MMD...

Indirect treatment comparison of the efficacy of long-acting injectable cabotegravir compared with lenacapavir for HIV pre-exposure prophylaxis

2026

INTRODUCTION: Long-acting injectable cabotegravir (hereafter referred to as cabotegravir) is the first long-acting injectable approved for pre-exposure prophylaxis (PrEP) based on the HPTN 083 and 084 trials. Long-acting injectable lenacapavir...

Oral manifestations in HIV-positive individuals under highly active antiretroviral therapy: A systematic review and meta-analysis of prevalence data

2026

This study aims to analytically explore the prevalence of oral manifestations in HIV-positive patients who are receiving or are not receiving highly active antiretroviral therapy (HAART). Electronic search was conducted...

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