SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Association between integrase strand transfer inhibitor use with insulin resistance and incident diabetes mellitus in persons living with HIV: A systematic review and meta-analysis

2023

Whether integrase strand transfer inhibitors (INSTIs) are associated with a higher risk of incident type 2 diabetes mellitus (DM) than other antiretroviral therapies (ART) needs to be established. MEDLINE, Embase,...

Gender differences in HIV knowledge among adolescents and young people in low-and middle-income countries: A systematic review

2023

OBJECTIVES: This review seeks to critically analyze studies assessing gender differences in HIV-related knowledge among adolescents and young people in low- and middle-income countries. METHODS: Using PRISMA guidelines and searching...

Assessing PrEP messaging and communication: A review of the qualitative literature

2023

Pre-exposure prophylaxis (PrEP) is a biomedical HIV prevention intervention approved by the FDA in 2012. Nevertheless, most sexual minority men (SMM) who could benefit from its use are not currently...

Barriers and facilitators related to COVID-19 vaccine acceptance and uptake among people living with HIV

2023

PURPOSE OF REVIEW: This review reports on the myriad barriers and facilitators related to COVID-19 vaccine hesitancy and factors contribution to uptake among people living with HIV (PLWH) globally published...

Immune reconstitution inflammatory syndrome, a controversial burden in the East African context: A systematic review and meta-analysis

2023

Introduction It is well established that starting antiretroviral therapy (ART) increases a patient’s life expectancy among HIV-positive individuals. Considering the HIV pandemic, the major concern is initiation of ARTs to...

Oral pre-exposure prophylaxis uptake and acceptability among men who have sex with men: A scoping review of the literature

2023

Despite the global effort to end the human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) epidemic as a global threat by 2030, the rate of new HIV infections worldwide...

Intersecting epidemics: COVID-19 and HIV in sub-Saharan Africa. A systematic review (2020–2022)

2023

There has been significant progress with regards to winning the fight against HIV globally, particularly due to the introduction of antiretroviral therapy (ART). COVID-19 threatened to derail gains in the...

A literature review on the adherence to screening guidelines for latent tuberculosis infection among persons living with HIV

2023

Human immunodeficiency virus (HIV) infection increases the risk of reactivation of latent tuberculosis infection (LTBI). Although antiretroviral therapy decreases the progression of LTBI to tuberculosis disease (TBD), persons living with...

Prevalence and risk factors for HIV infection in truck drivers: A systematic review of global evidence

2023

Transporting and driving long distances might be associated with an increased risk of contracting HIV in truck drivers, which is recognized as a link to network transmission of HIV among...

Inferring the multiplicity of founder variants initiating HIV-1 infection: A systematic review and individual patient data meta-analysis

2023

Background: HIV-1 infections initiated by multiple founder variants are characterised by a higher viral load and a worse clinical prognosis than those initiated with single founder variants, yet little is known...

An overview of programmatic indicators to monitor the roll-out of HIV preexposure prophylaxis

2023

Preexposure prophylaxis (PrEP) is increasingly implemented in national HIV prevention programmes through routine care. Monitoring will be vital to understand whether programmes succeed in engaging people into using PrEP appropriately,...

A scoping review of oral pre-exposure prophylaxis for cisgender and transgender adolescent girls and young women: What works and where do we go from here?

2023

Adolescent girls and young women (AGYW) are disproportionately affected by HIV, and oral pre-exposure prophylaxis (PrEP) can reduce HIV acquisition. The purpose of this scoping review was to synthesize results...

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