SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Non-pharmacological interventions for the prevention of sexually transmitted infections (STIs) in older adults: A systematic review

2023

BACKGROUND: STIs in older adults (adults aged 50 years and older) are on the rise due to variable levels of sex literacy and misperceived susceptibility to infections, among other factors....

The association between HIV infection and precancerous cervical lesion. A systematic review and meta-analysis of case-control studies

2023

BACKGROUND: The effect of human immunodeficiency virus (HIV) on precancerous cervical lesion is not consistent across studies. Besides to the variability in the presence of a significant association between HIV...

The use of non-invasive imaging modalities for the assessment of skeletal muscle quantity and quality in people with HIV: A narrative review

2023

BACKGROUND: People with HIV (PWH) are prone to mobility impairments and physical dysfunction, with the loss of skeletal muscle quantity and quality being a major contributor to the dysfunction. Assessment...

The association between intrapersonal resilience resources and quality of life among older persons living with HIV: A systematic review

2023

Despite positive improvements in health care, older persons living with HIV (PWH) still face psychosocial challenges and medical issues that affect their overall quality of life (QoL). Intrapersonal resilience resources...

Machine learning prediction models for clinical management of blood-borne viral infections: A systematic review of current applications and future impact

2023

BACKGROUND: Machine learning (ML) prediction models to support clinical management of blood-borne viral infections are becoming increasingly abundant in medical literature, with a number of competing models being developed for...

Stigmatizing and inaccessible: The perspectives of female sex workers on barriers to reproductive healthcare utilizationAA scoping review

2023

AIM: To systematically map the extent, range and nature of qualitative studies that explored female sex workers’ own perspectives on barriers to accessing reproductive healthcare services. DESIGN: A scoping review...

The impact of the M184V resistance mutation on treatment outcomes in patients with HIV infection: A systematic review and meta-analysis

2023

HIV is a global deliberating infectious disease. Of note, more than 36 million people living with HIV (PLHIV) with approximately newly diagnosed 1.5 million cases annually. M184V is a single...

Isoniazid preventive therapy for prevention of tuberculosis among people living with HIV in ethiopia: A systematic review of implementation and impacts

2023

BACKGROUND: Tuberculosis (TB) is a major cause of morbidity and mortality in people living with HIV (PLWHIV). Isoniazid preventive therapy (IPT) prevents TB in PLWHIV, but estimates of its effects...

Global prevalence of suicide in patients living with HIV/AIDS: A systematic review and meta-analysis

2023

Background: In fact, people living with HIV are at a greater risk of mental health disorders. Based on lack of necessary information in this area the present systematic review and meta-analysis...

Incidence of Pneumocystis pneumonia in immunocompromised patients without human immunodeficiency virus on intravenous pentamidine prophylaxis: A systematic review and meta-analysis

2023

BACKGROUND: Trimethoprim-sulfamethoxazole (TMP-SMX) is a first-line Pneumocystis pneumonia (PCP) prophylaxis agent, but monthly intravenous pentamidine (IVP) is used in immunocompromised hosts without human immunodeficiency virus (HIV) infection because IVP is...

Influencing factors and adverse outcomes of virologic rebound states in anti-retroviral-treated individuals with HIV infection

2023

Antiretroviral therapy (ART) aims to inhibit HIV replication, decrease CD4 T cell loss, and immune function recovery in order to reduce the morbidity and mortality associated with the infection. Treatment...

Association of hospitalization rate, mortality, and CD4 T cell count with comorbidity of COVID-19 and HIV: A systematic review and meta-analysis

2023

Epidemiological data demonstrate the greater severity of SARS-CoV-2 infection in HIV patients along with the more hospitalization, and mortality rates. Thus, this meta-analysis aimed to assess the possible differences in...

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