SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Machine learning prediction models for clinical management of blood-borne viral infections: A systematic review of current applications and future impact

2023

BACKGROUND: Machine learning (ML) prediction models to support clinical management of blood-borne viral infections are becoming increasingly abundant in medical literature, with a number of competing models being developed for...

Stigmatizing and inaccessible: The perspectives of female sex workers on barriers to reproductive healthcare utilizationAA scoping review

2023

AIM: To systematically map the extent, range and nature of qualitative studies that explored female sex workers’ own perspectives on barriers to accessing reproductive healthcare services. DESIGN: A scoping review...

The impact of the M184V resistance mutation on treatment outcomes in patients with HIV infection: A systematic review and meta-analysis

2023

HIV is a global deliberating infectious disease. Of note, more than 36 million people living with HIV (PLHIV) with approximately newly diagnosed 1.5 million cases annually. M184V is a single...

The mother-to-child transmission of HIV-1 and profile of viral reservoirs in pediatric population: A systematic review with meta-analysis of the Cameroonian studies

2023

Background: The mother-to-child transmission of HIV-1 (MTCT) remains on the major route of HIV-transmission among pediatric populations in Africa. Though a prevention of MTCT (PMTCT) high-priority country, data on the MTCT...

Incidence of Pneumocystis pneumonia in immunocompromised patients without human immunodeficiency virus on intravenous pentamidine prophylaxis: A systematic review and meta-analysis

2023

BACKGROUND: Trimethoprim-sulfamethoxazole (TMP-SMX) is a first-line Pneumocystis pneumonia (PCP) prophylaxis agent, but monthly intravenous pentamidine (IVP) is used in immunocompromised hosts without human immunodeficiency virus (HIV) infection because IVP is...

Influencing factors and adverse outcomes of virologic rebound states in anti-retroviral-treated individuals with HIV infection

2023

Antiretroviral therapy (ART) aims to inhibit HIV replication, decrease CD4 T cell loss, and immune function recovery in order to reduce the morbidity and mortality associated with the infection. Treatment...

Association of hospitalization rate, mortality, and CD4 T cell count with comorbidity of COVID-19 and HIV: A systematic review and meta-analysis

2023

Epidemiological data demonstrate the greater severity of SARS-CoV-2 infection in HIV patients along with the more hospitalization, and mortality rates. Thus, this meta-analysis aimed to assess the possible differences in...

The effectiveness and sustainability of peer support interventions for persons living with HIV: A realist synthesis

2023

BACKGROUND: Peer support is an important supplement to medical resources for persons living with HIV (PLHIV). However, previous studies have shown mixed results about intervention effects. It is necessary to...

Oral hyperpigmentation as an adverse effect of highly active antiretroviral therapy in HIV patients: A systematic review and pooled prevalence

2023

Background: Human Immunodeficiency Virus (HIV) infects patients via CD4+ cells which are later be destroyed subsequently causing the deteriotation of immune system. HIV generally manifests in the oral cavity as the...

Prevalence and incidence of stroke among people living with HIV: A systematic review and meta-analysis

2023

Objective: We aimed to obtain more precise estimates of stroke to address the wide variation of stroke burden among people with HIV (PWH) in different clinical settings. Design: Systematic review and meta-analysis....

Systematic review of alternative HIV preexposure prophylaxis care delivery models to improve preexposure prophylaxis services

2023

Objectives: To identify types, evidence, and study gaps of alternative HIV preexposure prophylaxis (PrEP) care delivery models in the published literature. Design: Systematic review and narrative synthesis. Methods: We searched in the US...

Adverse impact of intimate partner violence against HIV-positive women during pregnancy and post-partum: Results from a meta-analysis of observational studies

2023

Objectives: Intimate partner violence (IPV) against pregnant or human immunodeficiency virus (HIV)-positive women have been previously studied. However, data on the impact of IPV on HIV-positive pregnant women have not...

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