SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Understanding women’s knowledge, awareness, and perceptions of STIs/STDs in Asia: A scoping review

2023

OBJECTIVE: This study aimed to conduct a scoping review to collect current literature on the knowledge, awareness, and perception (KAP) of sexually transmitted infections/diseases (STIs/STDs) among women in Asia. METHODOLOGY:...

Clinical relevance of drug interactions in people living with human immunodeficiency virus on antiretroviral therapy—Update 2022: Systematic review

2023

BACKGROUND: The clinical outcomes of antiretroviral drugs may be modified through drug interactions; thus, it is important to update the drug interactions in people living with HIV (PLHIV). AIM: To...

The prognosis of progressive multifocal leukoencephalopathy in HIV/AIDS patients undergoing highly active antiretroviral treatment: A systematic review

2023

Progressive multifocal leukoencephalopathy (PML), a viral infection of the central nervous system (CNS), is most commonly associated with advanced HIV infection. Although the severe neurological conditions—PML and progressive multifocal leukoencephalopathy...

The burden of non-communicable diseases among people living with HIV in Sub-Saharan Africa: A systematic review and meta-analysis

2023

BACKGROUND: Non-communicable diseases (NCDs) are increasing among people living with HIV (PLHIV), especially in Sub-Saharan Africa (SSA). We determined the prevalence of NCDs and NCD risk factors among PLHIV in...

Neurological, behavioral, and pathophysiological characterization of the co-occurrence of substance use and HIV: A narrative review

2023

Combined antiretroviral therapy (cART) has greatly reduced the severity of HIV-associated neurocognitive disorders in people living with HIV (PLWH); however, PLWH are more likely than the general population to use...

Potentially inappropriate prescribing in older people living with HIV: A scoping review

2023

BACKGROUND: Antiretroviral therapy has transformed HIV from a progressive and often fatal infection to a chronic disease. Currently, people living with HIV (PLHIV) have near-normal life expectancy; however, they face...

Evaluation of HIV screening in hospital emergency services. Systematic review

2023

AIM: To evaluate HIV screening of people attending emergency services. DESIGN: Systematic review. DATA SOURCES: CINAHL Complete, Cochrane Library, Cuiden Plus, PubMed, PsycINFO, SCOPUS and Web of Science. REVIEW METHODS:...

A meta-analysis of gray matter volume abnormalities in HIV patients

2023

HIV infection is known to have significant effects on central nervous system. This study conducted a meta-analysis of whole voxel-based morphometry (VBM) in HIV patients (N=435) and HIV-uninfected controls (N=397)....

Tenofovir-induced renal dysfunction among HIV-infected patients: A systematic review

2023

Tenofovir disoproxil fumarate (TDF) is an antiretroviral drug widely used as part of antiretroviral therapy (ART) to treat human immunodeficiency virus (HIV-1) infection. Negative effects of tenofovir include impaired kidney...

Prevalence of delayed antiretroviral therapy initiation among people living with HIV: A systematic review and meta-analysis

2023

Objective HIV continues to be a global challenge. Key recommendations for HIV prevention and treatment are presented on rapid antiretroviral therapy (ART) initiation. However, several studies showed a high prevalence...

Immunogenicity and effectiveness of COVID-19 booster vaccination among people living with HIV: A systematic review and meta-analysis

2023

Background The effect of booster vaccinations with the coronavirus virus disease (COVID-19) vaccine on people living with HIV (PLWH) remains unknown. In this study, we aimed to investigate the immunogenicity...

HIV and mpox: A rapid review

2023

In this review, we discuss the history and epidemiology of mpox, prevention strategies, clinical characteristics and management, severity of mpox among persons with advanced HIV, and areas for future research...

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