Category Archives: Cardiovascular
Factors influencing treatment adherence in hypertension and HIV management in South Africa: A comparative literature review
BACKGROUND: Hypertension (HTN) is the most significant risk factor for cardiovascular disease (CVD) in South Africa (SA), with one in three people over the age of 25 suffering from HTN....
Association of HIV infection with cardiovascular pathology based on advanced cardiovascular imaging: A systematic review
Importance: HIV-associated cardiovascular disease is increasing in prevalence, but its mechanisms remain poorly understood. Objective: To systematically review data from advanced cardiovascular imaging studies evaluating computed tomographic coronary angiography, positron emission tomography...
A Systematic review exploring the effect of human immunodeficiency virus on cardiac diseases
Human immunodeficiency virus (HIV) primarily affects the immune systems, which, if progressed, will lead to acquired immunodeficiency syndrome (AIDS). Currently, there is no effective cure for the disease, and patients...
Incidence and risk factors of atrial fibrillation and atrial arrhythmias in people living with HIV: A systematic review and meta-analysis
BACKGROUND: Cardiovascular diseases in people living with HIV (PLWH) are becoming increasingly relevant as HIV/AIDS has become more treatable with the advent of highly efficacious antiretroviral therapy. Previous studies suggested...
Pulmonary arterial hypertension in patients infected with the human immunodeficiency virus
It is important to recognize and treat human immunodeficiency virus-associated pulmonary arterial hypertension (HIV-PAH) because of the associated morbidity and mortality. With the introduction of antiretroviral therapies (ART), improved survival...
Systematic review of spontaneous reports of myocarditis and pericarditis in transplant recipients and immunocompromised patients following COVID-19 mRNA vaccination
OBJECTIVES: To determine whether spontaneous reporting rates of myocarditis and pericarditis differed in immunocompromised patients compared with the whole population overall, and in terms of demographics, vaccine dose and time-to-onset....
Examining depression as a risk factor for cardiovascular disease in people with HIV: A systematic review
BACKGROUND: People with human immunodeficiency virus (HIV) have an increased risk of cardiovascular disease (CVD) not fully accounted for by traditional or HIV-specific risk factors. Successful management of HIV does...
Integrating care for diabetes and hypertension with HIV care in sub-Saharan Africa: A scoping review
INTRODUCTION: Although HIV continues to have a high prevalence among adults in sub-Saharan Africa (SSA), the burden of noncommunicable diseases (NCD) such as diabetes and hypertension is increasing rapidly. There...
Influence of statin therapy on the incidence of cardiovascular events, cancer, and all-cause mortality in people living with HIV: A meta-analysis
Background: Possible influences of statin therapy on the risk of cardiovascular events, cancer, and all-cause mortality in people living with HIV (PLWH) remain unclear. We performed a meta-analysis to systematically evaluate...
The likelihood of severe COVID-19 outcomes among PLHIV with various comorbidities: A comparative frequentist and Bayesian meta-analysis approach
INTRODUCTION: The SARS-CoV-2 virus can currently pose a serious health threat and can lead to severe COVID-19 outcomes, especially for populations suffering from comorbidities. Currently, the data available on the...
Sex differences in non-AIDS comorbidities among people with human immunodeficiency virus
Women are grossly underrepresented in human immunodeficiency virus (HIV) clinical and translational research. This is concerning given that people with HIV (PWH) are living longer, and thus accumulating aging-related non-AIDS...
