Category Archives: Epidemiology

Sero-positive HIV result disclosure to sexual partner in Ethiopia: A systematic review and meta-analysis

2019

BACKGROUND: The infection of HIV continues to be an important public health problem in Ethiopia. Disclosing own HIV positive result is crucial, and considered as a good indicator of behavior...

Different transmission routes and the risk of advanced HIV disease: A systematic review and network meta-analysis of observational studies

2019

Background: A substantial proportion of people living with HIV (PLHIV) present for care with advanced HIV disease (AHD), which may result in difficulty reaching the “90-90-90” target to end AIDS...

Global burden of hepatitis B infection in people living with HIV: A systematic review and meta-analysis

2019

BACKGROUND: This systematic review and meta-analysis was conducted to estimate the prevalence and burden of HBV infection in PLWH at global, regional, and national levels. METHODS: We searched of PubMed,...

Prevalence of HIV-seropositivity and associated impact on mortality among injured patients from low-and middle-income countries: A systematic review and meta-analysis

2017

BACKGROUND: Although HIV and injury contribute substantially to disease burdens in low-and middle-income countries (LMIC), their intersection is poorly characterized. OBJECTIVE: This systematic review assessed the prevalence and associated mortality...

Meta-analysis and systematic review of the efficacy and resistance for human immunodeficiency virus type 1 integrase strand transfer inhibitors

2019

Integrase strand transfer inhibitors (INSTIs) are the most recent class of antiretroviral drugs with potent and durable antiviral activity used to treat human immunodeficiency virus type 1 (HIV-1) infection. However,...

HIV prevalence among people who inject drugs (PWID) and related factors in Iran: A systematic review, meta-analysis and trend analysis

2019

AIMS: In Iran, injecting drug use has been the major route of human immunodeficiency virus (HIV) transmission. In order to control the HIV epidemic, a harm reduction program was initiated...

Clinical review report: Doravirine (Pifeltro)

2019

The objective of this systematic review was to evaluate the beneficial and harmful effects of doravirine, in combination with other antiretroviral medicinal products, for the treatment of HIV-1 infection in...

Comparing injecting and sexual risk behaviors of long-term injectors with new injectors: A meta-analysis

2019

The present meta-analysis aimed to investigate the effect of injection duration on injection and sexual high-risk behaviors among people who inject drugs (PWID), in order to inform development of intensive...

Getting youth PrEPared: Adolescent consent laws and implications for the availability of PrEP among youth in countries outside of the United States

2019

INTRODUCTION: Youth under the age of 25 are at high risk for HIV infection. While pre-exposure prophylaxis (PrEP) has the potential to curb new infections within this population, it is...

Scoping review of access to emergency contraception for sexual assault victims in emergency departments in the United States

2019

OBJECTIVE: We conducted a scoping review of the literature to assess the prevalence of hospital policies regarding emergency contraception (EC) and the frequency that U.S. emergency departments (EDs) provide EC...

Late presentation of HIV positive adults and its predictors to HIV/AIDS care in Ethiopia: A systematic review and meta-analysis

2019

INTRODUCTION: Late presentation to HIV/AIDS care which is attended by problems like, poor treatment outcomes, early development of opportunistic infections, increased healthcare costs, and mortality is a major problem in...

Recent levels and trends in HIV incidence rates among adolescent girls and young women in ten high-prevalence African countries: A systematic review and meta-analysis

2019

BACKGROUND: The roll-out of antiretroviral therapy (ART) has changed contexts of HIV risk, but the influence on HIV incidence among young women is not clear. We aimed to summarise direct...

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