Category Archives: Epidemiology and Determinants of Health
Fixed-dose antiretroviral combinations in children living with human immunodeficiency virus type 1 (HIV-1): A systematic review
Fixed-Dose antiretroviral Combinations (FDCs) are the most used drug regimes in adult patients with human-immunodeficiency virus 1 infection, since they increase adherence to antiretroviral therapy and enable good quality of...
Non-adherence to anti-retroviral therapy among adult people living with HIV in Ethiopia: Systematic review and meta-analysis
Human immunodeficiency virus remains a global public health problem. Despite efforts to determine the prevalence of non-adherence to ART and its predictors in Ethiopia, various primary studies presented inconsistent findings....
Prevalence of obesity, hypertension and diabetes among people living with HIV in South Africa: A systematic review and meta-analysis
Background HIV has become a manageable chronic condition due to the success and scale-up of antiretroviral therapy (ART). Globally, South Africa has the highest number of people living with HIV...
Enacted stigma influences bereavement coping among children orphaned by parental AIDS: A longitudinal study with network analysis
PURPOSE: The study aims to understand how enacted stigma influences bereavement coping at the style (scale) level and the specific pathways at the strategy (item) level. METHODS: The longitudinal data...
Association of naturally acquired type-specific HPV antibodies and subsequent HPV re-detection: Systematic review and meta-analysis
Background Understanding the role of naturally acquired (i.e., infection-induced) human papillomavirus (HPV) antibodies against reinfection is important given the high incidence of this sexually transmitted infection. However, the protective effect...
HIV prevalence in transgender populations and cisgender men who have sex with men in sub-Saharan Africa 2010–2022: A meta-analysis
Background and Aims Street children face a disproportionately higher risk of human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV) due to high‐risk sexual and drug use...
How much does HIV self-testing cost in low and middle income countries? A systematic review of evidence from economic studies
OBJECTIVES: HIV self-testing (HIVST) has been proposed as an innovative strategy to diagnose human immunodeficiency virus (HIV). While HIVST offers the potential to broaden accessibility of early HIV diagnosis and...
Demand creation and retention strategies for oral pre-exposure prophylaxis for HIV prevention among men who have sex with men and transgender women: A systematic review and meta-analysis
Background Men who have sex with men (MSM) and transgender women (TGW) have a disproportionately higher risk of human immunodeficiency virus (HIV) infection than other groups. Oral HIV pre-exposure prophylaxis...
Statistical methods applied for the assessment of the HIV cascade and continuum of care: A systematic scoping review
OBJECTIVES: This scoping review aims to identify and synthesise existing statistical methods used to assess the progress of HIV treatment programmes in terms of the HIV cascade and continuum of...
Geographic and population distributions of human immunodeficiency virus (HIV)-1 and HIV-2 circulating subtypes: A systematic literature review and meta-analysis (2010–2021)
BACKGROUND: HIV poses significant challenges for vaccine development due to its high genetic mutation and recombination rates. Understanding the distribution of HIV subtypes (clades) across regions and populations is crucial....
