Category Archives: People who use drugs

HIV and STI testing among Indigenous women and women who inject drugs

2016

Key take-home messages Rates of HIV and other sexually transmitted and bloodborne infections are high among Indigenous women and women who inject drugs. For women who use drugs, centres that...

Hepatitis C reinfection after successful treatment

2016

Key take-home messages HCV reinfection rates vary widely. Reinfection depends on the extent to which an individual engages in high risk activities after having achieved sustained virologic response through treatment....

Chest compressions and rescue breathing when administering naloxone in opioid overdose

2016

Key take-home messages Opioid overdoses cause respiratory failure (a reduction or stop in breathing), which can lead to cardiac arrest. In the event of a suspected opioid overdose, bystanders should...

Engaging law enforcement in harm reduction programs for people who inject drugs

2016

Key take-home messages Injection drug use is a major contributor to the spread of HIV and Hepatitis C in Canada. Laws and policing practices that govern injection drug use influence...

NARCANĀ® Nasal Spray efficacy for emergency treatment of opioid overdose

2018

Key take-home messages The administration of ready-to-use, needle-free concentrated NARCANĀ® Nasal Spray (containing 4mg of naloxone hydrochloride in low volume of 0.1 mL) results in pharmacokinetic parameters that either equal...

Improving PrEP implementation through multilevel interventions: A synthesis of the literature

2018

There are many challenges to accessing PrEP and thus low uptake in the United States. This review (2007-2017) of PrEP implementation identified barriers to PrEP and interventions to match those...

Predictors of human immunodeficiency virus (HIV) infection in primary care among adults living in developed countries: A systematic review

2018

BACKGROUND: Early diagnosis of human immunodeficiency virus (HIV) is important because antiretroviral therapies are more effective if infected individuals are diagnosed early. Diagnosis of HIV relies on laboratory testing and...

Injection drug use, HIV/HCV, and related services in nonurban areas of the United States: A systematic review

2018

BACKGROUND: Injection drug use (IDU) in nonurban areas of the United States is a growing public health concern, but there has been no comprehensive assessment of existing research on injection-related...

Integrated models of care for individuals with opioid use disorder: How do we prevent HIV and HCV?

2018

PURPOSE OF REVIEW: To describe models of integrated and co-located care for opioid use disorder (OUD), hepatitis C (HCV), and HIV. RECENT FINDINGS: The design and scale-up of multidisciplinary care...

Scoping out the literature on mobile needle and syringe programs-review of service delivery and client characteristics, operation, utilization, referrals, and impact

2018

BACKGROUND: Needle and syringe program (NSP) service delivery models encompass fixed sites, mobile services, vending machines, pharmacies, peer NSPs, street outreach, and inter-organizational agreements to add NSP services to other...

Strategies for improving the lives of US women aged 40 and above living with HIV/AIDS: An evidence map

2018

BACKGROUND: While in its early years the HIV epidemic affected primarily the male and the young, nowadays, the population living with HIV/AIDS is approximately 24% women, and its age composition...

HIV and viral hepatitis among imprisoned key populations

2018

Prisons and other closed facilities create opportunities for transmission of human immunodeficiency virus (HIV) and viral hepatitis during detention and after release. We conducted a systematic review and meta-analysis of...

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