Key take-home messages HCV affects people differently. Some are able to spontaneously clear the virus on their own; others develop chronic HCV infection that affects their health and requires treatment....
HIV and STI testing among Indigenous women and women who inject drugs
2016
Key take-home messages Rates of HIV and other sexually transmitted and bloodborne infections are high among Indigenous women and women who inject drugs. For women who use drugs, centres that...
Hepatitis C reinfection after successful treatment
2016
Key take-home messages HCV reinfection rates vary widely. Reinfection depends on the extent to which an individual engages in high risk activities after having achieved sustained virologic response through treatment....
Chest compressions and rescue breathing when administering naloxone in opioid overdose
2016
Key take-home messages Opioid overdoses cause respiratory failure (a reduction or stop in breathing), which can lead to cardiac arrest. In the event of a suspected opioid overdose, bystanders should...
Engaging law enforcement in harm reduction programs for people who inject drugs
2016
Key take-home messages Injection drug use is a major contributor to the spread of HIV and Hepatitis C in Canada. Laws and policing practices that govern injection drug use influence...
Improving PrEP implementation through multilevel interventions: A synthesis of the literature
2018
There are many challenges to accessing PrEP and thus low uptake in the United States. This review (2007-2017) of PrEP implementation identified barriers to PrEP and interventions to match those...
Predictors of human immunodeficiency virus (HIV) infection in primary care among adults living in developed countries: A systematic review
2018
BACKGROUND: Early diagnosis of human immunodeficiency virus (HIV) is important because antiretroviral therapies are more effective if infected individuals are diagnosed early. Diagnosis of HIV relies on laboratory testing and...
Injection drug use, HIV/HCV, and related services in nonurban areas of the United States: A systematic review
2018
BACKGROUND: Injection drug use (IDU) in nonurban areas of the United States is a growing public health concern, but there has been no comprehensive assessment of existing research on injection-related...
Integrated models of care for individuals with opioid use disorder: How do we prevent HIV and HCV?
2018
PURPOSE OF REVIEW: To describe models of integrated and co-located care for opioid use disorder (OUD), hepatitis C (HCV), and HIV. RECENT FINDINGS: The design and scale-up of multidisciplinary care...
HIV preexposure prophylaxis: A review
2018
Importance: About 40000 Americans and 2 million people worldwide are newly infected with HIV each year. The combination antiretroviral regimen, tenofovir disoproxil fumarate (TDF)/emtricitabine, taken as a single pill once...
Scoping out the literature on mobile needle and syringe programs-review of service delivery and client characteristics, operation, utilization, referrals, and impact
2018
BACKGROUND: Needle and syringe program (NSP) service delivery models encompass fixed sites, mobile services, vending machines, pharmacies, peer NSPs, street outreach, and inter-organizational agreements to add NSP services to other...
Strategies for improving the lives of US women aged 40 and above living with HIV/AIDS: An evidence map
2018
BACKGROUND: While in its early years the HIV epidemic affected primarily the male and the young, nowadays, the population living with HIV/AIDS is approximately 24% women, and its age composition...