Category Archives: General HIV+ population
Reviews on HIV+ people where the population is not specified
Clinical relevance of drug interactions in people living with human immunodeficiency virus on antiretroviral therapy—Update 2022: Systematic review
BACKGROUND: The clinical outcomes of antiretroviral drugs may be modified through drug interactions; thus, it is important to update the drug interactions in people living with HIV (PLHIV). AIM: To...
The impact of COVID-19 on HIV treatment of adolescents in sub-Saharan Africa: A scoping review
BACKGROUND: Adolescents living with HIV are a key population who are susceptible to poor health. The global coronavirus disease 2019 pandemic and widespread national COVID-19 restrictions has disrupted health service...
The effectiveness of e-health on reducing stigma, improving social support and quality of life among people living with HIV: A systematic review and meta-analysis of randomized controlled trials
Background: Many people living with HIV reported poor quality of life, which was primarily due to HIV-related stigma and the lack of social support. Compared with face-to-face interventions, e-health interventions are...
The association between intrapersonal resilience resources and quality of life among older persons living with HIV: A systematic review
Despite positive improvements in health care, older persons living with HIV (PWH) still face psychosocial challenges and medical issues that affect their overall quality of life (QoL). Intrapersonal resilience resources...
Systematic review on cumulative HIV viraemia among people living with HIV receiving antiretroviral treatment and its association with mortality and morbidity
BACKGROUND: We performed a systematic review to generate evidence on the association between cumulative human immunodeficiency virus (HIV) viraemia and health outcomes. METHODS: Quantitative studies reporting on HIV cumulative viraemia...
The prognosis of progressive multifocal leukoencephalopathy in HIV/AIDS patients undergoing highly active antiretroviral treatment: A systematic review
Progressive multifocal leukoencephalopathy (PML), a viral infection of the central nervous system (CNS), is most commonly associated with advanced HIV infection. Although the severe neurological conditions—PML and progressive multifocal leukoencephalopathy...
The burden of non-communicable diseases among people living with HIV in Sub-Saharan Africa: A systematic review and meta-analysis
BACKGROUND: Non-communicable diseases (NCDs) are increasing among people living with HIV (PLHIV), especially in Sub-Saharan Africa (SSA). We determined the prevalence of NCDs and NCD risk factors among PLHIV in...
Integration of female genital schistosomiasis into HIV/sexual and reproductive health and rights and neglected tropical diseases programmes and services: A scoping review
Female genital schistosomiasis (FGS) affects approximately 56 million women and girls across sub-Saharan Africa and is associated with up to a threefold increased prevalence of HIV. Integrating FGS with HIV...
Potentially inappropriate prescribing in older people living with HIV: A scoping review
BACKGROUND: Antiretroviral therapy has transformed HIV from a progressive and often fatal infection to a chronic disease. Currently, people living with HIV (PLHIV) have near-normal life expectancy; however, they face...
Tenofovir-induced renal dysfunction among HIV-infected patients: A systematic review
Tenofovir disoproxil fumarate (TDF) is an antiretroviral drug widely used as part of antiretroviral therapy (ART) to treat human immunodeficiency virus (HIV-1) infection. Negative effects of tenofovir include impaired kidney...
Prevalence of delayed antiretroviral therapy initiation among people living with HIV: A systematic review and meta-analysis
Objective HIV continues to be a global challenge. Key recommendations for HIV prevention and treatment are presented on rapid antiretroviral therapy (ART) initiation. However, several studies showed a high prevalence...