SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Measurement and evaluation of community engagement in complex, chronic medical conditions: HIV and obesity as exemplar conditions

2025

Objective To systematically review, describe, and compare quantitative measures of community engagement in obesity and HIV prevention research. Materials & Methods A systematic review adhering to PRISMA and PROSPERO guidelines...

Clinical trials of broadly neutralizing monoclonal antibodies in people living with HIV—A review

2025

Introduction HIV-1 remains a major global health challenge, impacting approximately 39 million people worldwide. Although antiretroviral therapy has substantially reduced HIV incidence and enhanced the quality of life for those living...

Immune responses to vaginal candidiasis in African women: A scoping review of cytokine profiles, T-cell activation, and gene expression

2025

Background Recent immunological studies of vaginal candidiasis in African populations have revealed complex host‒pathogen interactions with implications for therapeutic development and HIV acquisition risk. Objective This scoping review synthesized evidence...

HIV, hepatitis, and syphilis self-testing among adolescents and young adults: A systematic review and meta-analysis

2025

Background: Adolescents and young adults (AYA) make up a significant share of the world’s burden of HIV and other sexually transmitted infections (STI). Self-testing can increase testing coverage and strengthen the...

The prevalence of dyslipidemia and its correlation with anti-retroviral therapy among people living with HIV in China: A systematic review and meta-analysis

2025

Background Dyslipidemia, a risk factor of cardiovascular diseases, was a long-term adverse event of anti-retroviral drugs. Efavirenz (EFV) and lopinavir/ritonavir (LPV/r) were recommended and the widely used antiretroviral drugs while...

Studies on cognitive performance among older people living with HIV in eastern Europe and central Asia: A scoping review

2025

BACKGROUND: Despite the growth of the population of older people living with HIV (PLWH), data on cognitive disorders among older PLWH, particularly in low- and middle-income countries, are scarce. These...

Patient reported experiences in older adults living with

2025

Effective antiretroviral therapy has extended the life expectancy of people living with HIV and in Western countries, with 50% of individuals in Western countries now aged 50 or older. The...

HIV risk score and prediction model in the United States: A scoping review

2025

Human immunodeficiency virus (HIV) remains a public health issue in the U.S., affecting approximately 1.2 million individuals, many of whom are unaware of their infection status. This study reviews predictors...

Worldwide epidemiology of Cyclospora cayetanensis in HIV/AIDS patients: A systematic review and meta-analysis

2025

BACKGROUND: Cyclospora cayetanensis is a coccidian protozoan parasite belonging to the phylum Apicomplexa. This systematic review and meta-analysis aimed to assess the prevalence and risk factors of C. cayetanensis in...

Drug-drug interactions in transgender patients receiving antiretroviral and hormonal therapy: A systematic review of clinical studies and reports

2025

Transgender individuals, whose gender identity differs from their assigned sex at birth, often undergo pharmacotherapy, including hormone therapy (HT), as part of their gender-affirming care. This pharmacotherapy, particularly when combined...

Pre-exposure prophylaxis uptake among Black/African American men who have sex with other men in Midwestern, United States: A systematic review

2025

INTRODUCTION: Black/African American men who have sex with other men (BMSM) are disproportionately affected by HIV, experience significant disparities in HIV incidence, and face significant barriers to accessing HIV treatment...

Systematic review: HIV, aging, and housing—A North American perspective, 2012–2023

2024

Advances in anti-retroviral therapy (ART) have decreased mortality rates and subsequently led to a rise in the number of HIV-positive people living longer. The housing experiences of this new population...

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