Category Archives: General HIV+ population
Reviews on HIV+ people where the population is not specified
Comparison of treatment-emergent resistance-associated mutations and discontinuation due to adverse events among integrase strand transfer inhibitor-based single-tablet regimens and cabotegravir + rilpivirine for the treatment of virologically suppressed people with HIV: A systematic literature review and network meta-analysis
Objective This study evaluated rates of treatment‐emergent resistance‐associated mutations (TE‐RAMs) and discontinuation due to adverse events (DC‐AEs) across integrase strand transfer inhibitor (INSTI)‐based single‐tablet regimens and injectable cabotegravir + rilpivirine...
Reporting and handling of missing data in published studies of co-morbid hypertension and diabetes among people living with HIV/AIDS: A systematic review
BACKGROUND: As hypertension and diabetes emerge as co-morbidities among people living with HIV/AIDS (PLWH), the need for robust epidemiological research to inform policy and action is imperative. Proper reporting and...
Global research landscape of HIV and Kaposi’s sarcoma: A visualized bibliometric analysis
BACKGROUND: Human immunodeficiency virus (HIV) infection remains a significant global health challenge, with Kaposi’s sarcoma (KS) being one of the most common AIDS-defining cancers. This study aimed to investigate the...
Efficacy and safety of systematic corticosteroids treatment among patients with HIV and tuberculosis: A systematic review and meta-analysis of randomized controlled trials
INTRODUCTION: The efficacy and safety of corticosteroids in patients with human immunodeficiency virus (HIV) and tuberculosis (TB) remain controversial. METHOD: PubMed, Embase, Web of Science, and the Cochrane Database were...
Prevalence of HIV drug resistance among patients experiencing first-line treatment failure in Ethiopia: A systematic review and meta-analysis
Background The emergence of human immunodefiency virus (HIV) drug resistance presents a substantial challenge. Alternatives for effective treatment regimens are limited, and treatment strategies are complicated. Although a number of...
Are Candida albicans isolates from people living with HIV more resistant to antifungals? A systematic review and meta-analysis
People living with HIV (PLHIV) often require antifungal medications for the treatment or prevention of infections, which may contribute to the emergence of resistant Candida albicans strains. This systematic review...
Evolving patterns of macrolide and fluoroquinolone resistance in Mycoplasma genitalium: An updated systematic review and meta-analysis
Background: Over the past 5 years, since publication of the initial review, studies have provided additional data on macrolide and fluoroquinolone resistance in Mycoplasma genitalium, including data from regions previously lacking...
HIV-1 drug resistance in children and implications for pediatric treatment strategies: A systematic review and meta-analysis
Introduction Failure in the prevention of mother-to-child HIV transmission (PMTCT) and pediatric treatment challenges led to pretreatment drug resistance (PDR) and acquired drug resistance (ADR) in children with HIV (CWHIV)....
The association between HIV infection and carotid intima-media thickness in the era of antiretroviral therapy: A meta-analysis
Atherosclerosis remains a leading cause of mortality globally, and this is worse in people living with HIV (PLHIV). While the administration of antiretroviral therapy (ART) in this population has significant...
