Category Archives: Treatment

Use of stated preference methods in HIV treatment and prevention research in the United States: A systematic review

2023

Stated preference (SP) methods are increasingly being applied to HIV-related research and continuously provide researchers with health utility scores of select healthcare products or services that populations consider important. Following...

Systemic treatment and radiotherapy for patients with non-small cell lung cancer (NSCLC) and HIV infection — A systematic review

2023

Lung cancer is the most common non-AIDS defining cancer among people living with HIV (PLWH), but there is a paucity of data regarding the efficacy and toxicity of radiotherapy and...

Efficacy, safety and tolerability of Biktarvy in HIV-1 infection: A scoping review

2023

Background: Biktarvy is approved for use in HIV-1 infection in both treatment-naïve and treatment-experienced individuals, after a series of successful phase III trials. However, studies on real-world evidence on its efficacy,...

Associations between HIV disclosure and HIV care continuum outcomes among men who have sex with men living with HIV: Systematic review and meta-analysis

2023

The objective of this study is to synthesize the existing empirical literature and perform a systematic review and meta-analysis on the relationship between HIV disclosure and engagement in the HIV...

Prevalence and determinants of opportunistic infections among HIV-infected adults receiving antiretroviral therapy in Ethiopia: A systematic review and meta-analysis

2023

BACKGROUND: Reliable data on the burden of opportunistic infections (OIs) after the initiation of antiretroviral therapy (ART) is critical for planning health services and reducing OI-related morbidity and Background: Reliable data...

Interventions to enhance medication adherence in pregnancy — A systematic review

2023

Background: Sub-optimal medication adherence in pregnant women with chronic disease and pregnancy-related indications has the potential to adversely affect maternal and perinatal outcomes. Adherence to appropriate medications is advocated during and...

Characteristics of psychosocial interventions to improve ART adherence in people living with HIV: A systematic review

2023

The HIV/AIDS pandemic continues to be a significant global public health crisis. The main HIV/AIDS treatment is the antiretroviral therapy (ART), which is highly effective but depends on the patient’s...

Prevalence of undernutrition and associated factors among adults taking antiretroviral therapy in sub-Saharan Africa: A systematic review and meta-analysis

2023

BACKGROUND: Undernutrition (Body Mass Index < 18.5 kg/m2) is a common problem and a major cause of hospital admission for patients living with HIV. Though sub-Saharan Africa is the most...

Barriers and facilitators to maintaining a high level of polypharmacy adherence in people living with HIV: A scoping review

2023

Objectives: With the prolongation of life span and increasing incidence of comorbidities, polypharmacy has become a challenge for people living with HIV/AIDS (PLWH). This review aimed to identify barriers and...

Does telehealth affect the adherence to ART among patients with HIV? A systematic review and meta-analysis

2023

Background Several studies have shown different effects of telehealth interventions on adherence to Antiretroviral therapy (ART) among people living with HIV. This study conducted a meta-analysis of Randomized Controlled Trials...

Immediate treatment for recent hepatitis C infection in people with high-risk behaviors: A systematic review and meta-analysis

2023

BACKGROUND AND AIMS: Direct-acting antivirals (DAAs) are almost exclusively approved for the treatment of chronic HCV. This poses a significant barrier to the treatment of recently acquired HCV because of...

Health economic analyses of latent tuberculosis infection screening and preventive treatment among people living with HIV in lower tuberculosis incidence settings: A systematic review

2023

Introduction: In lower tuberculosis (TB) incidence countries (<100 cases/100,000/year), screening and preventive treatment (PT) for latent TB infection (LTBI) among people living with HIV (PLWH) is often recommended, yet guidelines...

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