SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Association of HIV infection with cardiovascular pathology based on advanced cardiovascular imaging: A systematic review

2022

Importance: HIV-associated cardiovascular disease is increasing in prevalence, but its mechanisms remain poorly understood. Objective: To systematically review data from advanced cardiovascular imaging studies evaluating computed tomographic coronary angiography, positron emission tomography...

Priorities in the implementation of partner services for HIV/STIs in high-income nations: A narrative review of evidence and recommendations

2022

Partner notification (PN) remains a crucial prevention tool to reduce sexually transmitted infection (STI) transmission and prevent STI-related morbidity. Although there have been a variety of different approaches taken to...

Diagnosis, treatment, and prevention of HIV infection among detainees: A review of the literature

2022

Detainees are one of the most vulnerable populations to human immunodeficiency virus (HIV). This is mostly caused by the lack of knowledge on the topic among the inmates; the lack...

Human immunodeficiency virus infection promotes human papillomavirus-mediated anal squamous carcinogenesis: An immunologic and pathobiologic review

2022

BACKGROUND: Anal squamous cell carcinoma (SCC) is a rare gastrointestinal malignancy with rising incidence, both in the United States and internationally. The primary risk factor for anal SCC is human...

Systematic review of sex differences in the relationship between hormones and depression in HIV

2022

BACKGROUND: Major depressive disorder is the most common neuropsychiatric comorbidity of human immunodeficiency virus (HIV), and women are more frequently affected in the general population and among those with HIV....

Treatments for AIDS/HIV-related Kaposi sarcoma: A systematic review of the literature

2022

BACKGROUND: Treatment guidelines are not well established in AIDS-related Kaposi sarcoma (KS). OBJECTIVE: We aim to review the evidence on efficacy of treatments for AIDS-related Kaposi sarcoma. METHODS: We searched...

HIV-related intersectional stigma and discrimination measurement: State of the science

2022

Background. Across settings, individuals from populations that are multiply stigmatized are at increased risk of HIV and experience worse HIV treatment outcomes. As evidence expands on how intersecting stigmatized identities and...

Kidney function in tenofovir disoproxil fumarate-based oral pre-exposure prophylaxis users: A systematic review and meta-analysis of published literature and a multi-country meta-analysis of individual participant data

2022

Background: Previous WHO guidance on tenofovir disoproxil fumarate-based oral pre-exposure prophylaxis (PrEP) suggests measuring creatinine levels at PrEP initiation and regularly afterwards, which might represent barriers to PrEP implementation and uptake....

Queering poppers literature: A critical interpretive synthesis of health sciences research on alkyl nitrite use and Canadian policy

2022

BACKGROUND: Poppers (alkyl nitrites) are vasodilators used by many gay, bisexual, and other men who have sex with men (GBMSM) to relieve pain, enhance pleasure, and facilitate penetration during sex....

How the term ‘self-management’ is used in HIV research in low- and middle-income countries: A scoping review

2022

This scoping review assessed how the term ‘self-management’ (SM) is used in peer-reviewed literature describing HIV populations in low- and middle-income countries (LMIC). This review followed the Preferred Reporting Items...

The role of the social determinants of health on engagement in physical activity or exercise among adults living with HIV: A scoping review

2022

Physical activity (PA) and exercise are an effective rehabilitation strategy to improve health outcomes among people living with HIV (PLWH). However, engagement in exercise among PLWH can vary. Our aim...

US Black cisgender women and pre-exposure prophylaxis for human immunodeficiency virus prevention: A scoping review

2022

Background: Black cisgender women in the United States experience a disproportionate burden of human immunodeficiency virus acquisition. Pre-exposure prophylaxis is an effective oral daily medication that reduces the risk of...

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